Stage-dependent remodeling of projections to motor cortex in ALS mouse model revealed by a new variant retrograde-AAV9

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Stage-dependent remodeling of projections to motor cortex in ALS mouse model revealed by a new variant retrograde-AAV9

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im August 2018 veröffentlichter wissenschaftlicher Artikel

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scientific article published on 23 August 2018

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wetenschappelijk artikel

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наукова стаття, опублікована в серпні 2018

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Stage-dependent remodeling of ...... a new variant retrograde-AAV9

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Stage-dependent remodeling of ...... a new variant retrograde-AAV9

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Stage-dependent remodeling of ...... a new variant retrograde-AAV9

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Stage-dependent remodeling of ...... a new variant retrograde-AAV9

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Stage-dependent remodeling of ...... a new variant retrograde-AAV9

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Stage-dependent remodeling of ...... a new variant retrograde-AAV9

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Stage-dependent remodeling of ...... a new variant retrograde-AAV9

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Albert C Ludolph

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Barbara Commisso

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David Bayer

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Karl Varadi

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Lingjun Ding

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Martin Gorges

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Oliver J Müller

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Tobias M Boeckers

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P2860

Revealing the secrets of neuronal circuits with recombinant rabies virus technology

Correspondence of the brain's functional architecture during activation and rest

Increased functional connectivity common to symptomatic amyotrophic lateral sclerosis and those at genetic risk

Long-range neuronal circuits underlying the interaction between sensory and motor cortex.

Predicting human resting-state functional connectivity from structural connectivity

Wild-type and mutant SOD1 share an aberrant conformation and a common pathogenic pathway in ALS.

Deficits in axonal transport precede ALS symptoms in vivo.

Axonal transport deficits and degeneration can evolve independently in mouse models of amyotrophic lateral sclerosis.

Long-distance axonal transport of AAV9 is driven by dynein and kinesin-2 and is trafficked in a highly motile Rab7-positive compartment.

The problem of functional localization in the human brain.

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scholarly article

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10.7554/ELIFE.36892

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English

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Jan Kassubek

Francesco Roselli

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2018-08-23T00:00:00Z

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30136928

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amyotrophic lateral sclerosis

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6125125

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