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Discovery of Novel Small-Molecule Inhibitors of BRD4 Using Structure-Based Virtual ScreeningRapid Discovery of Pyrido[3,4-d]pyrimidine Inhibitors of Monopolar Spindle Kinase 1 (MPS1) Using a Structure-Based Hybridization ApproachCharacterisation of CCT271850, a selective, oral and potent MPS1 inhibitor, used to directly measure in vivo MPS1 inhibition vs therapeutic efficacySynthesis of mucin-type O-glycan probes as aminopropyl glycosides.Synthesis and evaluation of two series of 4'-aza-carbocyclic nucleosides as adenosine A2A receptor agonists.Reactivity of cyclic sulfamidates towards phosphonate-stabilised enolates: synthesis and applications of alpha-phosphono lactams.Regioselective and enantiospecific synthesis of the HSP co-inducer arimoclomol from chiral glycidyl derivatives.Expanding the scope of fused pyrimidines as kinase inhibitor scaffolds: synthesis and modification of pyrido[3,4-d]pyrimidines.High Proliferation Rate and a Compromised Spindle Assembly Checkpoint Confers Sensitivity to the MPS1 Inhibitor BOS172722 in Triple-Negative Breast CancersAchieving In Vivo Target Depletion through the Discovery and Optimization of Benzimidazolone BCL6 Degraders
P50
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P50
description
researcher ORCID ID = 0000-0001-8429-2546
@en
wetenschapper
@nl
name
Hannah Woodward
@ast
Hannah Woodward
@en
Hannah Woodward
@es
Hannah Woodward
@nl
type
label
Hannah Woodward
@ast
Hannah Woodward
@en
Hannah Woodward
@es
Hannah Woodward
@nl
prefLabel
Hannah Woodward
@ast
Hannah Woodward
@en
Hannah Woodward
@es
Hannah Woodward
@nl
P106
P31
P496
0000-0001-8429-2546