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The M-Ras-RA-GEF-2-Rap1 pathway mediates tumor necrosis factor-alpha dependent regulation of integrin activation in splenocytesTargeted deletion of the H-ras gene decreases tumor formation in mouse skin carcinogenesisSignaling complex formation of phospholipase Cbeta4 with metabotropic glutamate receptor type 1alpha and 1,4,5-trisphosphate receptor at the perisynapse and endoplasmic reticulum in the mouse brainDefective vascular morphogenesis and mid-gestation embryonic death in mice lacking RA-GEF-1A gene-targeted mouse model for chorea-acanthocytosisDopamine D2 receptor plays a critical role in cell proliferation and proopiomelanocortin expression in the pituitaryDorsal telencephalon-specific RA-GEF-1 knockout mice develop heterotopic cortical mass and commissural fiber defectComprehensive behavioral phenotyping of a new Semaphorin 3 F mutant mouseIn vivo imaging visualizes discoid platelet aggregations without endothelium disruption and implicates contribution of inflammatory cytokine and integrin signaling.Farnesylation of retinal transducin underlies its translocation during light adaptation.Dynamic distribution of muscle-specific calpain in mice has a key role in physical-stress adaptation and is impaired in muscular dystrophy.A crucial role for CDC42 in senescence-associated inflammation and atherosclerosis.Deletion of Rac1GTPase in the Myeloid Lineage Protects against Inflammation-Mediated Kidney Injury in Mice.Territories of heterologous inputs onto Purkinje cell dendrites are segregated by mGluR1-dependent parallel fiber synapse eliminationConditional mutant mice using tetracycline-controlled gene expression system in the brain.FSP27 contributes to efficient energy storage in murine white adipocytes by promoting the formation of unilocular lipid droplets.Requirement of the immediate early gene vesl-1S/homer-1a for fear memory formation.Dephosphorylated parafibromin is a transcriptional coactivator of the Wnt/Hedgehog/Notch pathways.Essential mesenchymal role of small GTPase Rac1 in interdigital programmed cell death during limb development.Odor-induced persistent discharge of mitral cells in the mouse olfactory bulb.Use of human methylation arrays for epigenome research in the common marmoset (Callithrix jacchus).Role of the guanine nucleotide exchange factor in Akt2-mediated plasma membrane translocation of GLUT4 in insulin-stimulated skeletal muscle.A critical role of the small GTPase Rac1 in Akt2-mediated GLUT4 translocation in mouse skeletal muscle.Generation of RGS8 null mutant mice by Cre/loxP system.Semaphorin 3F confines ventral tangential migration of lateral olfactory tract neurons onto the telencephalon surface.A possible aid in targeted insertion of large DNA elements by CRISPR/Cas in mouse zygotes.Subcellular and subsynaptic localization of group I metabotropic glutamate receptors in the monkey subthalamic nucleus.Generation of cloned mice from adult neurons by direct nuclear transfer.Selective activation of mTORC1 signaling recapitulates microcephaly, tuberous sclerosis, and neurodegenerative diseases.Cdc42 is crucial for facial and palatal formation during craniofacial development.Development of the somatosensory cortex, the cerebellum, and the main olfactory system in Semaphorin 3F knockout mice.Roles of glutamate receptor delta 2 subunit (GluRdelta 2) and metabotropic glutamate receptor subtype 1 (mGluR1) in climbing fiber synapse elimination during postnatal cerebellar development.Loss of adaptability of horizontal optokinetic response eye movements in mGluR1 knockout mice.Extracellular calcium controls the dynamic range of neuronal metabotropic glutamate receptor responses.mGluR1 in cerebellar Purkinje cells is required for normal association of temporally contiguous stimuli in classical conditioning.Rac1 in cortical projection neurons is selectively required for midline crossing of commissural axonal formation.Synaptically driven endocannabinoid release requires Ca2+-assisted metabotropic glutamate receptor subtype 1 to phospholipase Cbeta4 signaling cascade in the cerebellum.Rac1-Mediated Activation of Mineralocorticoid Receptor in Pressure Overload-Induced Cardiac Injury.Temporal requirement of dystroglycan glycosylation during brain development and rescue of severe cortical dysplasia via gene delivery in the fetal stage.Hyperactive mTOR induces neuroendocrine differentiation in prostate cancer cell with concurrent up-regulation of IRF1.
P50
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researcher ORCID ID = 0000-0002-8192-0778
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wetenschapper
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Atsu Aiba
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Atsu Aiba
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Atsu Aiba
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P106
P108
P31
P496
0000-0002-8192-0778