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Human aldolase A natural mutants: relationship between flexibility of the C-terminal region and enzyme functionFunctional analysis of the promoter of the mitochondrial phosphate carrier human gene: identification of activator and repressor elements and their transcription factorsDifferential expression and cellular localization of ZNF224 and ZNF255, two isoforms of the Krüppel-like zinc-finger protein family.KRAB-Zinc Finger Proteins: A Repressor Family Displaying Multiple Biological Functions.ZNF224: Structure and role of a multifunctional KRAB-ZFP protein.The hematopoietic tumor suppressor interferon regulatory factor 8 (IRF8) is upregulated by the antimetabolite cytarabine in leukemic cells involving the zinc finger protein ZNF224, acting as a cofactor of the Wilms' tumor gene 1 (WT1) protein.WT1-mediated repression of the proapoptotic transcription factor ZNF224 is triggered by the BCR-ABL oncogeneToxicity of aflatoxin B1 towards the vitamin D receptor (VDR).The Complex Role of the ZNF224 Transcription Factor in Cancer.Role of WT1-ZNF224 interaction in the expression of apoptosis-regulating genes.The Kruppel-like zinc finger protein ZNF224 recruits the arginine methyltransferase PRMT5 on the transcriptional repressor complex of the aldolase A gene.The Krüppel-like zinc-finger protein ZNF224 represses aldolase A gene transcription by interacting with the KAP-1 co-repressor protein.Characterization of a silencer that modulates transcription of the human distal aldolase A promoter.Growth-arrested dependence of aldolase A L-type mRNA expression in rodent cell lines.KAP1 is a Novel Substrate for the Arginine Methyltransferase PRMT5.PKC-dependent phosphorylation of the p97 repressor regulates the transcription of aldolase A L-type promoter.Role of ZNF224 in cell growth and chemoresistance of chronic lymphocitic leukemia.WT1 protein is a transcriptional activator of the antiapoptotic bag3 gene.Multiple Control Elements Regulate Transcription from the Most Distal Promoter of Human Aldolase A GeneIn vivo activity of the most proximal promoter of the human aldolase A ene and analysis of transcriptional control elementsZNF224 is a transcriptional repressor of AXL in chronic myeloid leukemia cells
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description
researcher ORCID ID = 0000-0002-0267-379X
@en
wetenschapper
@nl
name
Paola Costanzo
@ast
Paola Costanzo
@en
Paola Costanzo
@es
Paola Costanzo
@nl
type
label
Paola Costanzo
@ast
Paola Costanzo
@en
Paola Costanzo
@es
Paola Costanzo
@nl
prefLabel
Paola Costanzo
@ast
Paola Costanzo
@en
Paola Costanzo
@es
Paola Costanzo
@nl
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56236378200
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0000-0002-0267-379X