about
Metabotropic glutamate receptor 5 is a coreceptor for Alzheimer aβ oligomer bound to cellular prion proteinAlzheimer amyloid-β oligomer bound to postsynaptic prion protein activates Fyn to impair neurons.Brivaracetam, but not ethosuximide, reverses memory impairments in an Alzheimer's disease mouse model.Therapeutic molecules and endogenous ligands regulate the interaction between brain cellular prion protein (PrPC) and metabotropic glutamate receptor 5 (mGluR5).Fyn inhibition rescues established memory and synapse loss in Alzheimer mice.Prion-Protein-interacting Amyloid-β Oligomers of High Molecular Weight Are Tightly Correlated with Memory Impairment in Multiple Alzheimer Mouse Models.Metabotropic glutamate receptor 5 couples cellular prion protein to intracellular signalling in Alzheimer's diseaseOpposing effects of progranulin deficiency on amyloid and tau pathologies via microglial TYROBP network.Early Activation of Experience-Independent Dendritic Spine Turnover in a Mouse Model of Alzheimer's Disease.Metabotropic Glutamate Receptor 5 Is a Coreceptor for Alzheimer Aβ Oligomer Bound to Cellular Prion ProteinCorrelation of the shoulder girdle asymmetry with the limb skeleton asymmetry in Xenopus laevis
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description
researcher ORCID ID = 0000-0003-0435-8141
@en
wetenschapper
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name
Mikhail A Kostylev
@ast
Mikhail A Kostylev
@en
Mikhail A Kostylev
@es
Mikhail A Kostylev
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type
label
Mikhail A Kostylev
@ast
Mikhail A Kostylev
@en
Mikhail A Kostylev
@es
Mikhail A Kostylev
@nl
prefLabel
Mikhail A Kostylev
@ast
Mikhail A Kostylev
@en
Mikhail A Kostylev
@es
Mikhail A Kostylev
@nl
P106
P108
P1153
55355414600
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P496
0000-0003-0435-8141