A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours - Wikidata - wikimedia - TriplyDB

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

http://www.wikidata.org/entity/Q59059617

about

Time-dependent stabilization of hypoxia inducible factor-1α by different intracellular sources of reactive oxygen species Wnt-responsive cancer stem cells are located close to distorted blood vessels and not in hypoxic regions in a p53-null mouse model of human breast cancer.A phase I study of the human monoclonal anti-NRP1 antibody MNRP1685A in patients with advanced solid tumors.A Phase Ib study evaluating MNRP1685A, a fully human anti-NRP1 monoclonal antibody, in combination with bevacizumab and paclitaxel in patients with advanced solid tumors.A novel 3D human glioblastoma cell culture system for modeling drug and radiation responses.Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma.Xiaotan Sanjie decoction attenuates tumor angiogenesis by manipulating Notch-1-regulated proliferation of gastric cancer stem-like cells.Histone deacetylase 1/Sp1/microRNA-200b signaling accounts for maintenance of cancer stem-like cells in human lung adenocarcinoma SOX2 is a cancer-specific regulator of tumour initiating potential in cutaneous squamous cell carcinoma.Tenascin-W is a better cancer biomarker than tenascin-C for most human solid tumors Endothelial cells provide a notch-dependent pro-tumoral niche for enhancing breast cancer survival, stemness and pro-metastatic properties.Epidermal expression of neuropilin 1 protects murine keratinocytes from UVB-induced apoptosis.Multipotent cancer stem cells derived from human malignant peritoneal mesothelioma promote tumorigenesis.Celecoxib alleviates tamoxifen-instigated angiogenic effects by ROS-dependent VEGF/VEGFR2 autocrine signaling Identification of a population of epidermal squamous cell carcinoma cells with enhanced potential for tumor formation.MicroRNA-410 reduces the expression of vascular endothelial growth factor and inhibits oxygen-induced retinal neovascularization.Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer.Deflection of vascular endothelial growth factor action by SS18-SSX and composite vascular endothelial growth factor- and chemokine (C-X-C motif) receptor 4-targeted therapy in synovial sarcoma The Proton-Sensing G-Protein Coupled Receptor GPR4 Promotes Angiogenesis in Head and Neck Cancer Neuropilin 1 expression correlates with the Radio-resistance of human non-small-cell lung cancer cells.Autocrine platelet-derived growth factor-vascular endothelial growth factor receptor-related (Pvr) pathway activity controls intestinal stem cell proliferation in the adult Drosophila midgut ARTEMIN promotes de novo angiogenesis in ER negative mammary carcinoma through activation of TWIST1-VEGF-A signalling.Mitotic spindle (DIS)orientation and DISease: cause or consequence?Autocrine functions of VEGF in breast tumor cells: adhesion, survival, migration and invasion.GLI1 regulates a novel neuropilin-2/α6β1 integrin based autocrine pathway that contributes to breast cancer initiation.β -Elemene-Attenuated Tumor Angiogenesis by Targeting Notch-1 in Gastric Cancer Stem-Like Cells.A novel association of neuropilin-1 and MUC1 in pancreatic ductal adenocarcinoma: role in induction of VEGF signaling and angiogenesis.New paradigms and future challenges in radiation oncology: an update of biological targets and technology.Slug promoted vasculogenic mimicry in hepatocellular carcinoma.Metronomic chemotherapy prevents therapy-induced stromal activation and induction of tumor-initiating cells.Cancer stem cells, a fuzzy evolving concept: a cell population or a cell property?CD133+ cancer stem cells promoted by VEGF accelerate the recurrence of hepatocellular carcinoma.Global expression profile of tumor stem-like cells isolated from MMQ rat prolactinoma cell.Dynamic Interactions Between Cancer Stem Cells And Their Stromal Partners.De-repression of the RAC activator ELMO1 in cancer stem cells drives progression of TGFβ-deficient squamous cell carcinoma from transition zones.Aberrant microRNA expression likely controls RAS oncogene activation during malignant transformation of human prostate epithelial and stem cells by arsenic.Keratinocyte stem cells and the targets for nonmelanoma skin cancer.Formation and regulation of the cancer stem cell niche.Stem cells of the human epidermis and their niche: composition and function in epidermal regeneration and carcinogenesis.Interaction between regulatory T cells and cancer stem cells.

P2860

Q28484609-45AE8D12-C0AE-427B-9AFE-D841EB486AB7 Q30581875-6CD90D4A-4A2C-45D9-A2A7-1F27BFC13351 Q33413739-8A40168C-D651-42B3-BB63-5CDB70A6D1F6 Q33413979-9D384D39-CB14-4132-800C-53D625D1AC82 Q33777423-6DD97F78-E679-4B31-8E15-62088707BE72 Q33856474-9EFEA6E4-C393-4556-BD67-E9414A53A69E Q34255543-69A51D3E-61BB-46AB-A66A-73815678AA32 Q34287415-908D51B9-2795-4E45-91C2-0E62C4F941D8 Q34396696-218C77B5-830E-4A9A-AFAE-CE177A8B6660 Q34402770-575CE1C5-2B73-48FF-A505-E35094B5D07F Q34473290-34FFC304-C0DA-430B-971F-9B9A530C6175 Q34515970-BAD572C8-AD1F-483E-8051-E68BF2A20CE3 Q34534660-FF5EA2ED-36E4-42E8-8D68-FEAD7AC4032D Q34753820-1110CD5A-EB6C-4692-864D-4E2C54AC2967 Q35078367-F8D1C524-DEB1-40CB-9EE7-3F9A580E16DF Q35159008-52AC04AE-2EE8-4531-ADA1-B7DAD865311F Q35358840-468410FB-68A5-42C2-A06C-2FF5AF893CC9 Q35713658-AA9B34F8-DCC7-4872-980C-8B87E3F3C095 Q35989833-98024CD1-5075-4A30-82C9-2CBAD0860680 Q36057518-09B600AA-B4D8-4375-9068-D0D91D4C9DCB Q36201720-50177242-DABE-4C6F-8F70-15E73AAE8327 Q36416481-B101CBA3-4F6E-41C9-8CB9-D6BDCF3C562C Q36486600-F1BE8A07-DA7F-4E66-9730-4A1438918461 Q36542090-C93F1FB0-BD3F-4E76-B1C8-B9083461729F Q36771302-7BE2570B-E79D-4BCE-9B9F-BB184DC39DFE Q36848635-46202BB2-6DC7-401A-9D3E-896A4C670DCE Q37124065-9567395B-1DFA-4611-BD3F-6E0A7095CAF0 Q37160539-4E5D62EF-6E4A-47C0-8A18-63B617A3B6F4 Q37191031-58DB7713-EA36-4EAB-9302-95CA89DB769E Q37500307-6C4421F6-60AF-4F15-99B5-619F366CF408 Q37525819-C7430E72-400D-48BA-8C26-E6A0D28EBB44 Q37612276-5E86ABD7-65CA-4A56-AEF4-994697A6A0C4 Q37615467-4AFDF139-C7CF-4DD2-9C09-0A9A38DB59A1 Q37641700-F54EA482-8075-408C-81B4-E4A2CD7AAD26 Q37656680-FC7AD9B4-1232-45AE-A048-181FE8560F22 Q37669900-688356EA-9A17-4748-AB67-62342C6E0B3A Q37972666-E2CE87AF-A744-4D6E-AD61-CEBDFA1FAF54 Q37993598-15B4DDE1-8EAD-406C-A3CF-093C754EEA47 Q37998450-EE1C637E-9BE9-4D1C-B38E-D5F1CF55026F Q38010643-EA2B33D4-11DB-463A-8A39-7DBBFADD423D

P2860

A vascular niche and a VEGF–Nrp1 loop regulate the initiation and stemness of skin tumours

http://www.wikidata.org/entity/Q59059617

description

article publié dans la revue scientifique Nature

@fr

scientific article published in Nature

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в Nature в жовтні 2011

@uk

name

A vascular niche and a VEGF–Nr ...... n and stemness of skin tumours

@en

A vascular niche and a VEGF–Nr ...... n and stemness of skin tumours

@nl

type

label

A vascular niche and a VEGF–Nr ...... n and stemness of skin tumours

@en

A vascular niche and a VEGF–Nr ...... n and stemness of skin tumours

@nl

prefLabel

A vascular niche and a VEGF–Nr ...... n and stemness of skin tumours

@en

A vascular niche and a VEGF–Nr ...... n and stemness of skin tumours

@nl

P1433

Q59059617-FDF86297-5F0B-48ED-8555-25D96C39959B

P1476

Q59059617-D97972A2-E9C6-4BB0-8FE0-D84F2FAE46B5

P2093

Q59059617-02C9A5E6-4800-4BF5-990B-065940D1A9F3

Q59059617-08CAA1A1-B74B-4D18-86E8-35AE624361DD

Q59059617-0E5C6B94-624A-4AB4-AA7F-8A860297F65D

Q59059617-11032354-FD86-4D9D-87D7-3349383A20E4

Q59059617-13D87EE0-BAA6-42CD-ABA2-C6531F9117A4

Q59059617-3622ED19-C2BE-4C4F-B78B-D82092236652

Q59059617-45156462-25FC-4F17-B98C-25148F7E0285

Q59059617-52D673D6-6A07-431F-8320-3DACA7B089A1

Q59059617-68B87136-0F27-44F6-97D9-7A7953270300

Q59059617-6F348BFB-CE9A-4C83-8423-962DA4DF43DE

P2860

Q59059617-01452D0F-F994-466D-8F5A-2211402563F8

Q59059617-0A44B321-C6D2-488C-B2B2-125492D20DF3

Q59059617-0EF05953-BDD9-4346-94E0-380E3BE6843F

Q59059617-18FFD583-3805-422A-A0F8-83DFE3A118CF

Q59059617-1975EFA0-14EC-4DDD-A45B-7DB8B8374877

Q59059617-22877E81-298F-4F12-BBED-90829A312FF7

Q59059617-285A9FA4-C645-402B-9CD3-32BA42898893

Q59059617-3371CF99-B8C3-4233-AC58-B2AC57F27B35

Q59059617-624A15F6-0EE7-497C-87D7-FFAD29BD7E62

Q59059617-6B8AA2C6-FE74-4BCE-89D6-D0B0D48F66D3

P2888

Q59059617-AED19C2E-38AB-41BA-8341-32C8AD59FC3C

P304

Q59059617-6F78C395-072E-48E7-8A36-271E7CD63B00

P31

Q59059617-E90E7870-4313-41A8-82C6-E57EBF917952

P356

Q59059617-9B36E424-0578-4B58-9277-622C518C6CE2

P407

Q59059617-4A66221C-32B0-40AF-8566-036DC1511940

P433

Q59059617-4BC28228-85AE-4480-94BE-DB7D66864449

P478

Q59059617-97E7B0DB-D2AB-499E-B3B3-FEF99D883ADB

P50

Q59059617-F083A3F5-4BDF-49EC-8C01-7E9BD0557299

P577

Q59059617-BA50EB1E-910F-4069-B0A4-90A25B1155E9

P6179

Q59059617-BE06C43D-A3B7-4929-8232-7ED4D76F50EB

P698

Q59059617-81B6B900-D42B-4384-AFAA-07ED361280F2

P356

P1433

P1476

A vascular niche and a VEGF-Nr ...... n and stemness of skin tumours

@en

P2093

Amélie Caauwe

http://www.w3.org/2001/XMLSchema#string

Anna Kuchnio

http://www.w3.org/2001/XMLSchema#string

Aurélie Candi

http://www.w3.org/2001/XMLSchema#string

Benjamin Beck

http://www.w3.org/2001/XMLSchema#string

Benjamin Drogat

http://www.w3.org/2001/XMLSchema#string

Cédric Blanpain

http://www.w3.org/2001/XMLSchema#string

Gaelle Lapouge

http://www.w3.org/2001/XMLSchema#string

Gregory Driessens

http://www.w3.org/2001/XMLSchema#string

Guilhem Mascre

http://www.w3.org/2001/XMLSchema#string

Jody J Haigh

http://www.w3.org/2001/XMLSchema#string

P2860

Blocking neuropilin-1 function has an additive effect with anti-VEGF to inhibit tumor growth

Neuropilin-1 is expressed by endothelial and tumor cells as an isoform-specific receptor for vascular endothelial growth factor

Hyperproliferation and defects in epithelial polarity upon conditional ablation of alpha-catenin in skin

A perivascular niche for brain tumor stem cells

Tumor angiogenesis

Asymmetric cell divisions promote stratification and differentiation of mammalian skin.

Monoclonal antibodies targeting the VEGF receptor-2 (Flk1/KDR) as an anti-angiogenic therapeutic strategy.

Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones.

Cutaneous squamous-cell carcinoma.

Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors.

P2888

P304

399-403

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1038/NATURE10525

http://www.w3.org/2001/XMLSchema#string

P407

P433

7369

http://www.w3.org/2001/XMLSchema#string

P478

478

http://www.w3.org/2001/XMLSchema#string

P50

Steven Goossens

P577

2011-10-19T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P6179

1011100488

http://www.w3.org/2001/XMLSchema#string

P698

22012397

http://www.w3.org/2001/XMLSchema#string