Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

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Combination immuno-oncology therapy with pembrolizumab, an anti-PD-1 monoclonal antibody targeting immune evasion, and standard chemotherapy for patients with the squamous and non-squamous subtypes of non-small cell lung cancer

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Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

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http://www.wikidata.org/entity/Q59070397

description

article publié dans la revue scientifique Nature

@fr

scientific article published in Nature

@en

wetenschappelijk artikel

@nl

наукова стаття, опублікована в Nature в серпні 2018

@uk

name

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

@en

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

@nl

type

Item

label

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

@en

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

@nl

prefLabel

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

@en

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

@nl

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Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

@en

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Alexander C Huang

http://www.w3.org/2001/XMLSchema#string

Beike Wang

http://www.w3.org/2001/XMLSchema#string

Bin Wu

http://www.w3.org/2001/XMLSchema#string

E John Wherry

http://www.w3.org/2001/XMLSchema#string

Gang Chen

http://www.w3.org/2001/XMLSchema#string

Gao Zhang

http://www.w3.org/2001/XMLSchema#string

Giorgos C Karakousis

http://www.w3.org/2001/XMLSchema#string

Gordon Mills

http://www.w3.org/2001/XMLSchema#string

Haidong Dong

http://www.w3.org/2001/XMLSchema#string

Honghong Sun

http://www.w3.org/2001/XMLSchema#string

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Rab27a and Rab27b control different steps of the exosome secretion pathway

The ESCRT machinery

Regulation of immune responses by extracellular vesicles

Tumor-associated B7-H1 promotes T-cell apoptosis: a potential mechanism of immune evasion

Isolation and characterization of exosomes from cell culture supernatants and biological fluids

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

T cell receptor antagonist peptides induce positive selection

Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles

PD-1 blockade induces responses by inhibiting adaptive immune resistance

Tumor-derived microvesicles promote regulatory T cell expansion and induce apoptosis in tumor-reactive activated CD8+ T lymphocytes.

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s41586-018-0392-8

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382-386

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scholarly article

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10.1038/S41586-018-0392-8

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English

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7718

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560

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Meenhard Herlyn

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2018-08-01T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

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30089911

http://www.w3.org/2001/XMLSchema#string

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immunosuppression

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6095740

http://www.w3.org/2001/XMLSchema#string

Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

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Exosomal PD-L1 contributes to immunosuppression and is associated with anti-PD-1 response

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P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

P932

P356

P1433

P1476

P2093

P2860

P2888

P304

P31

P356

P407

P433

P478

P50

P577

P698

P921

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