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Local chromatin microenvironment determines DNMT activity: from DNA methyltransferase to DNA demethylase or DNA dehydroxymethylaseCrustacean hyperglycaemic hormone (CHH)-like peptides and CHH-precursor-related peptides from pericardial organ neurosecretory cells in the shore crab, Carcinus maenas, are putatively spliced and modified products of multiple genesHyperlipidemia and atherosclerosis associated with liver disease in ferrochelatase-deficient miceMaternal diabetes leads to unphysiological high lipid accumulation in rabbit preimplantation embryos.Sexually dimorphic characteristics of the small intestine and colon of prepubescent C57BL/6 miceThe breast cancer resistance protein protects against a major chlorophyll-derived dietary phototoxin and protoporphyria.Endothelium-dependent relaxation and angiotensin II sensitivity in experimental preeclampsia.Maternal Western-style high fat diet induces sex-specific physiological and molecular changes in two-week-old mouse offspringInfluence of relative NK-DC abundance on placentation and its relation to epigenetic programming in the offspringThe Gut Microbiota and their Metabolites: Potential Implications for the Host Epigenome.The ABC of hepatic and intestinal cholesterol transport.Cholesterol transport by the placenta: placental liver X receptor activity as a modulator of fetal cholesterol metabolism?Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development.Maternal exposure to a Western-style diet causes differences in intestinal microbiota composition and gene expression of suckling mouse pups.The role of nutrition on epigenetic modifications and their implications on health.The role of maternal-fetal cholesterol transport in early fetal life: current insights.Lipotoxicity and the role of maternal nutrition.Impact of maternal cholesterol metabolism on ovarian follicle development and fertility.Pharmacogenetics of drug-induced birth defects: the role of polymorphisms of placental transporter proteins.Inhibiting Cholesterol Absorption During Lactation Programs Future Intestinal Absorption of Cholesterol in Adult Mice.Preeclampsia As Modulator of Offspring Health.Immune-modulatory effects of syncytiotrophoblast extracellular vesicles in pregnancy and preeclampsia.The peroxisome proliferator-activated receptors under epigenetic control in placental metabolism and fetal development.Individualized lipid-lowering therapy to further reduce residual cardiovascular risk.The liver X receptor (LXR) and its target gene ABCA1 are regulated upon low oxygen in human trophoblast cells: a reason for alterations in preeclampsia?Stimulation of murine biliary cholesterol secretion by thyroid hormone is dependent on a functional ABCG5/G8 complex.The liver X-receptor gene promoter is hypermethylated in a mouse model of prenatal protein restriction.Experimental preeclampsia in rats affects vascular gene expression patterns.Mdr P-glycoproteins are not essential for biliary excretion of the hydrophobic heme precursor protoporphyrin in a griseofulvin-induced mouse model of erythropoietic protoporphyria.Continuous enteral administration can overcome the limited capacity to absorb glucose in rats with methotrexate-induced gastrointestinal mucositis.Increased hepatobiliary and fecal cholesterol excretion upon activation of the liver X receptor is independent of ABCA1.Association between methylation of the SLC6A4 promoter region in peripheral blood leukocytes and methylation in amygdala tissue.Cyclosporin a and enterohepatic circulation of bile salts in rats: decreased cholate synthesis but increased intestinal reabsorption.Sitosterolemia in ABC-transporter G5-deficient mice is aggravated on activation of the liver-X receptor.Increased fecal neutral sterol loss upon liver X receptor activation is independent of biliary sterol secretion in mice.The fetal programming effect of prenatal smoking on Igf1r and Igf1 methylation is organ- and sex-specific.Prenatal exposure to tobacco smoke sex dependently influences methylation and mRNA levels of the Igf axis in lungs of mouse offspring.Parental vitamin D deficiency during pregnancy is associated with increased blood pressure in offspring via Panx1 hypermethylation.Early micronutrient supplementation protects against early stress-induced cognitive impairments.A New Enzyme-linked Sorbent Assay (ELSA) to Quantify Syncytiotrophoblast Extracellular Vesicles in Biological Fluids.
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researcher ORCID ID = 0000-0002-9305-4045
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wetenschapper
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0000-0002-9305-4045