about
Characterization of 2'-fluoro-RNA aptamers that bind preferentially to disease-associated conformations of prion protein and inhibit conversion.Delivery is key: lessons learnt from developing splice-switching antisense therapiesPathogenetic mechanisms of amyloid A amyloidosis.Development of therapeutic splice-switching oligonucleotides.Exon skipping of hepatic APOB pre-mRNA with splice-switching oligonucleotides reduces LDL cholesterol in vivo.Distinct patterns of heparan sulphate in pancreatic islets suggest novel roles in paracrine islet regulation.Antisense-mediated exon-skipping to induce gene knockdown.Multigene RNA vector based on coronavirus transcription.Dieter C. Gruenert, PhD (1949-2016).Methionine 129 variant of human prion protein oligomerizes more rapidly than the valine 129 variant: implications for disease susceptibility to Creutzfeldt-Jakob disease.Validation of oligonucleotide-mediated gene editing.The presence of valine at residue 129 in human prion protein accelerates amyloid formation.
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P50
description
researcher ORCID ID = 0000-0001-9702-9974
@en
name
Petra Disterer
@ast
Petra Disterer
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Petra Disterer
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Petra Disterer
@nl
type
label
Petra Disterer
@ast
Petra Disterer
@en
Petra Disterer
@es
Petra Disterer
@nl
prefLabel
Petra Disterer
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Petra Disterer
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Petra Disterer
@es
Petra Disterer
@nl
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6507497319
P31
P496
0000-0001-9702-9974