about
Repair on the go: E. coli maintains a high proliferation rate while repairing a chronic DNA double-strand breakBacterial genome instabilityResolution of joint molecules by RuvABC and RecG following cleavage of the Escherichia coli chromosome by EcoKIRecombination at double-strand breaks and DNA ends: conserved mechanisms from phage to humans.The SbcCD protein of Escherichia coli is related to two putative nucleases in the UvrA superfamily of nucleotide-binding proteins.DNA tandem repeat instability in the Escherichia coli chromosome is stimulated by mismatch repair at an adjacent CAG·CTG trinucleotide repeatA perfect palindrome in the Escherichia coli chromosome forms DNA hairpins on both leading- and lagging-strands.Cloning and sequencing of four structural genes for the Na(+)-translocating NADH-ubiquinone oxidoreductase of Vibrio alginolyticus.Branch migration prevents DNA loss during double-strand break repairRepair of DNA covalently linked to protein.Prevent and Cure: RPA Cooperates with Mre11-Sae2 in DNA Secondary Structure Repair.E. coli SbcCD and RecA control chromosomal rearrangement induced by an interrupted palindrome.Chromosomal directionality of DNA mismatch repair in Escherichia coliRecG Directs DNA Synthesis during Double-Strand Break Repair.Quantitative genomic analysis of RecA protein binding during DNA double-strand break repair reveals RecBCD action in vivoChemical Evolution of a Bacterial Proteome.Nucleolytic processing of a protein-bound DNA end by the E. coli SbcCD (MR) complex.A novel mode of nuclease action is revealed by the bacterial Mre11/Rad50 complex.RecG controls DNA amplification at double-strand breaks and arrested replication forks.DIR: a novel DNA rearrangement associated with inverted repeats.Long inverted repeat transiently stalls DNA replication by forming hairpin structures on both leading and lagging strands.Expansion of CAG repeats in Escherichia coli is controlled by single-strand DNA exonucleases of both polarities.SbcCD regulation and localization in Escherichia coli.Division-induced DNA double strand breaks in the chromosome terminus region of Escherichia coli lacking RecBCD DNA repair enzyme.Pulsed-field gel electrophoresis of bacterial chromosomes.Non-random segregation of sister chromosomes in Escherichia coli.Structural and functional similarities between the SbcCD proteins of Escherichia coli and the RAD50 and MRE11 (RAD32) recombination and repair proteins of yeast.Broken replication forks trigger heritable DNA breaks in the terminus of a circular chromosome.Overexpression of the single-stranded DNA-binding protein (SSB) stabilises CAG*CTG triplet repeats in an orientation dependent manner.DNA palindromes adopt a methylation-resistant conformation that is consistent with DNA cruciform or hairpin formation in vivo.SbcCD causes a double-strand break at a DNA palindrome in the Escherichia coli chromosome.Overexpression, purification, and characterization of the SbcCD protein from Escherichia coli.The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination.Dynamics of RecA-mediated repair of replication-dependent DNA breaks.Replication Fork Breakage and Restart in Escherichia coliRecBCD coordinates repair of two ends at a DNA double-strand break, preventing aberrant chromosome amplificationTwo opposing effects of mismatch repair on CTG repeat instability in Escherichia coliHolliday junctions, heteroduplex DNA and map expansion: a commentary on ‘A mechanism for gene conversion in fungi’ by Robin HollidayEvidence for two preferred hairpin folding patterns in d(CGG)·d(CCG) repeat tracts in vivo 1 1Edited by I. TinocoReplication strand preference for deletions associated with DNA palindromes
P50
Q27334553-74AA34E3-9880-4DDE-946A-68B586893A5FQ28657639-1CBFBD62-0CE3-46EC-8F01-665D1F1B9AA6Q33490983-B4D25003-CD65-4743-9B7A-71F6425DBB5DQ34108141-0E8C1C6A-70DE-42EA-93AF-EE14BD23F8F9Q34297559-6B2BC299-F0B6-4B04-9582-6D5D3AC081EAQ34450103-C565F869-C5F1-43B3-952B-A9D117EF406FQ34579770-E6802089-77EC-4834-8553-672E9D6E3AD7Q34722725-D63355E1-3012-4E84-AC5E-8695DCB35A39Q35221144-580AAA10-B533-4B58-BF9D-7EE3F0BC3C56Q35669018-7244923F-A09B-4F5D-99F6-DF53DF05B4BAQ35834401-31FD532E-68DD-4F55-B254-AA096A6AC0FDQ35859652-24192C03-02C1-43B6-A34F-069385F7E286Q35910253-09791784-4D07-4FB8-AD5E-F3C5B5DC0282Q35922661-804B4039-B984-45F4-A4D2-069CF287CE31Q36008202-8AB25BA3-CCC4-4FD1-B51B-A23BB421177AQ36664160-084B6A5E-24A5-411A-81EC-CFCC016E495FQ38353277-E3DFCFB6-6040-4A51-8FD3-AF00DFD56D08Q38934134-7CF43F78-4878-45ED-8D66-A42F83841AC9Q39117161-396AE3AE-0C65-4422-B5E2-98846F02013CQ39718954-00CC8854-3536-49B1-B161-57AE2DADFA3EQ40135706-AAD856A1-F2B7-4B68-A9FD-7DEB17799317Q42086935-3AD9D612-338D-46A0-816F-22FC985C8073Q42637108-1926E40C-6CA0-4015-A133-123C66975D59Q42652312-5E6EB2A1-CF19-4682-B4DF-CA2F3D51ED9FQ44945374-7B2239B3-10F2-468F-B443-E833FEEA00EBQ46275146-B5F39E26-1213-44B8-8C96-6BDCE7BF121CQ48070792-FE2D1CA3-8429-4922-9349-0BD4B4185BDFQ52664387-774D48D9-0705-4EA1-ABBA-3454C323FEECQ53062249-0CD735C0-03D2-47D2-930D-72D871F39AFCQ54162559-B2D49DE6-78F4-4B89-868F-0F70DE6AB1CFQ54425189-2A2078DB-400F-4E23-AEDE-870B2F338E23Q54560199-35398FC4-EFB5-4E07-9C1D-D8BFB7C2DE7BQ54592220-5FB0A112-475D-4097-B2AC-834E0AAAA18EQ55414779-1A811071-83B2-457C-9687-337B7EE01B53Q57753866-BA2D7416-1E73-4738-A258-8049B49717B5Q64389445-0192EBC6-641B-49B5-8928-8C7C6513D749Q64448324-0239E8BF-C809-436C-AA91-494CE103F1A5Q64461701-432F0F0A-F7F2-4971-BEB8-0D04D27A6457Q64461707-E71B2DF0-CC0F-4520-A2E7-1AD877CF7A11Q64461708-1D0FC8F0-ABD4-48EA-9FDD-D64B046DDF4C
P50
description
researcher ORCID ID = 0000-0003-4964-6913
@en
wetenschapper
@nl
name
David Leach
@ast
David Leach
@en
David Leach
@es
David Leach
@nl
type
label
David Leach
@ast
David Leach
@en
David Leach
@es
David Leach
@nl
prefLabel
David Leach
@ast
David Leach
@en
David Leach
@es
David Leach
@nl
P106
P21
P31
P496
0000-0003-4964-6913