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Are Microglial Cells the Regulators of Lymphocyte Responses in the CNS?Histochemical demonstration of purine nucleoside phosphorylase (PNPase) in microglial and astroglial cells of adult rat brainIncrease in Th17 and T-reg lymphocytes and decrease of IL22 correlate with the recovery phase of acute EAE in rat.Differential modulation of TREM2 protein during postnatal brain development in mice.Astrocyte-targeted production of interleukin-6 reduces astroglial and microglial activation in the cuprizone demyelination model: Implications for myelin clearance and oligodendrocyte maturation.Increased levels of proinflammatory cytokines in the aged rat brain attenuate injury-induced cytokine response after excitotoxic damage.Alterations in microglial phenotype and hippocampal neuronal function in transgenic mice with astrocyte-targeted production of interleukin-10.Astrocyte-targeted production of IL-10 induces changes in microglial reactivity and reduces motor neuron death after facial nerve axotomy.Expression of inducible nitric oxide synthase and cyclooxygenase-2 after excitotoxic damage to the immature rat brain.Activated microglial cells acquire an immature dendritic cell phenotype and may terminate the immune response in an acute model of EAE.Triflusal posttreatment inhibits glial nuclear factor-kappaB, downregulates the glial response, and is neuroprotective in an excitotoxic injury model in postnatal brain.RGD domains neuroprotect the immature brain by a glial-dependent mechanism.Immunotoxic depletion of microglia in mouse hippocampal slice cultures enhances ischemia-like neurodegeneration.Substantial migration of SVZ cells to the cortex results in the generation of new neurons in the excitotoxically damaged immature rat brain.Survivin and heat shock protein 25/27 colocalize with cleaved caspase-3 in surviving reactive astrocytes following excitotoxicity to the immature brain.Reduced cuprizone-induced cerebellar demyelination in mice with astrocyte-targeted production of IL-6 is associated with chronically activated, but less responsive microglia.Distinct spatial and temporal activation of caspase pathways in neurons and glial cells after excitotoxic damage to the immature rat brain.Delayed neurodegeneration and early astrogliosis after excitotoxicity to the aged brain.Stat3 and NFkappaB glial expression after excitotoxic damage to the postnatal brain.Dynamics of microglia in the developing rat brain.Expression of purine metabolism-related enzymes by microglial cells in the developing rat brain.Time course of proliferation and elimination of microglia/macrophages in different neurodegenerative conditions.Antioxidant Cu/Zn SOD: expression in postnatal brain progenitor cells.NF-kappaB and IkappaBalpha expression following traumatic brain injury to the immature rat brain.The microglial reaction in spinal cords of jimpy mice is related to apoptotic oligodendrocytes.Tomato lectin histochemistry for microglial visualization.Purine Signaling and Microglial Wrapping.CD4 microglial expression correlates with spontaneous clinical improvement in the acute Lewis rat EAE model.Expression of 27 kDa heat shock protein (Hsp27) in immature rat brain after a cortical aspiration lesion.STAT3 and NFkappaB activation precedes glial reactivity in the excitotoxically injured young cortex but not in the corresponding distal thalamic nuclei.Cytochemical demonstration of TPPase in myelinated fibers in the central and peripheral nervous system of the rat.Effects of astrocyte-targeted production of interleukin-6 in the mouse on the host response to nerve injuryEffect of zinc, copper and glucocorticoids on metallothionein levels of cultured neurons and astrocytes from rat brainMicroglia Detection by Enzymatic HistochemistryMorphology and distribution of microglial cells in the young and adult mouse cerebellumReduction of the microglial cell number in rat primary glial cell cultures by exogenous addition of dibutyryl cyclic adenosine monophosphateDevelopment of microglia in the prenatal rat hippocampusDemonstration of poly-N-acetyl lactosamine residues in ameboid and ramified microglial cells in rat brain by tomato lectin bindingAbnormal expression of the proliferating cell nuclear antigen (PCNA) in the spinal cord of the hypomyelinated Jimpy mutant miceOral administration of the anti-inflammatory substance triflusal results in the downregulation of constitutive transcription factor NF-kappaB in the postnatal rat brain
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researcher ORCID ID = 0000-0002-1860-3980
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wetenschapper
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Berta González
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Berta González
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Berta González
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Berta González
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Berta González
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Berta González
@en
Berta González
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Berta González
@nl
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Berta González
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Berta González
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Berta González
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Berta González
@nl
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lccn-n98012423