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High resolution in vivo bioluminescent imaging for the study of bacterial tumour targetingThe Impact of the Gut Microbiota on Drug Metabolism and Clinical OutcomeDevelopment of multiple strain competitive index assays for Listeria monocytogenes using pIMC; a new site-specific integrative vectorRegulation of host weight gain and lipid metabolism by bacterial bile acid modification in the gutContribution of three bile-associated loci, bsh, pva, and btlB, to gastrointestinal persistence and bile tolerance of Listeria monocytogenes.Human neutrophil clearance of bacterial pathogens triggers anti-microbial γδ T cell responses in early infectionRole for HtrA in stress induction and virulence potential in Listeria monocytogenes.Identification and disruption of BetL, a secondary glycine betaine transport system linked to the salt tolerance of Listeria monocytogenes LO28.Mutations in the listerial proB gene leading to proline overproduction: effects on salt tolerance and murine infectionCharacterization of the groESL operon in Listeria monocytogenes: utilization of two reporter systems (gfp and hly) for evaluating in vivo expression.Multiple deletions of the osmolyte transporters BetL, Gbu, and OpuC of Listeria monocytogenes affect virulence and growth at high osmolarity.Two-Dimensional Polyacrylamide Gel Electrophoresis Analysis of the Acid Tolerance Response in Listeria monocytogenes LO28Bile salt hydrolase activity in probiotics.Investigation of the mechanisms by which Listeria monocytogenes grows in porcine gallbladder bile.Divergent evolution of the activity and regulation of the glutamate decarboxylase systems in Listeria monocytogenes EGD-e and 10403S: roles in virulence and acid toleranceInfluence of internalin A murinisation on host resistance to orally acquired listeriosis in mice.A postgenomic appraisal of osmotolerance in Listeria monocytogenesA mariner transposon-based signature-tagged mutagenesis system for the analysis of oral infection by Listeria monocytogenes.Adaptive acid tolerance response in Listeria monocytogenes: isolation of an acid-tolerant mutant which demonstrates increased virulenceAcid adaptation of Listeria monocytogenes can enhance survival in acidic foods and during milk fermentation.Altered FXR signalling is associated with bile acid dysmetabolism in short bowel syndrome-associated liver disease.A mutant of Listeria monocytogenes LO28 unable to induce an acid tolerance response displays diminished virulence in a murine modelImproved luciferase tagging system for Listeria monocytogenes allows real-time monitoring in vivo and in vitro.Bile Acid Modifications at the Microbe-Host Interface: Potential for Nutraceutical and Pharmaceutical Interventions in Host Health.Evidence for plasmid-mediated salt tolerance in the human gut microbiome and potential mechanisms.Short bowel syndrome (SBS)-associated alterations within the gut-liver axis evolve early and persist long-term in the piglet model of short bowel syndrome.Signature tagged mutagenesis in the functional genetic analysis of gastrointestinal pathogens.Construction of p16Slux, a novel vector for improved bioluminescent labeling of gram-negative bacteria.Gastrointestinal phase of Listeria monocytogenes infection.Unconjugated Bile Acids Influence Expression of Circadian Genes: A Potential Mechanism for Microbe-Host CrosstalkThe interaction between bacteria and bile.Disease-Associated Changes in Bile Acid Profiles and Links to Altered Gut Microbiota.Tools for functional postgenomic analysis of listeria monocytogenes.Functional and comparative metagenomic analysis of bile salt hydrolase activity in the human gut microbiome.CesRK, a two-component signal transduction system in Listeria monocytogenes, responds to the presence of cell wall-acting antibiotics and affects beta-lactam resistance.M-cells: origin, morphology and role in mucosal immunity and microbial pathogenesis.Acid stress responses in Listeria monocytogenes.Understanding the mechanisms by which probiotics inhibit gastrointestinal pathogens.The interaction between Listeria monocytogenes and the host gastrointestinal tract.Listeria monocytogenes: survival and adaptation in the gastrointestinal tract.
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description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-2385-8192
@en
name
Cormac G Gahan
@ast
Cormac G Gahan
@en
Cormac G Gahan
@nl
type
label
Cormac G Gahan
@ast
Cormac G Gahan
@en
Cormac G Gahan
@nl
prefLabel
Cormac G Gahan
@ast
Cormac G Gahan
@en
Cormac G Gahan
@nl
P106
P31
P496
0000-0003-2385-8192