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Characterization of a Gene Expression Signature in Normal Rat Prostate Tissue Induced by the Presence of a Tumor Elsewhere in the Organ.High Lysyl Oxidase (LOX) in the Non-Malignant Prostate Epithelium Predicts a Poor Outcome in Prostate Cancer Patient Managed by Watchful Waiting.Adaptive (TINT) Changes in the Tumor Bearing Organ Are Related to Prostate Tumor Size and Aggressiveness.Extratumoral Heme Oxygenase-1 (HO-1) Expressing Macrophages Likely Promote Primary and Metastatic Prostate Tumor GrowthAggressive rat prostate tumors reprogram the benign parts of the prostate and regional lymph nodes prior to metastasis.Extracellular Vesicles from Metastatic Rat Prostate Tumors Prime the Normal Prostate Tissue to Facilitate Tumor Growth.Inhibition of Lysyl Oxidase and Lysyl Oxidase-Like Enzymes Has Tumour-Promoting and Tumour-Suppressing Roles in Experimental Prostate Cancer.Reduced number of CD169+ macrophages in pre-metastatic regional lymph nodes is associated with subsequent metastatic disease in an animal model and with poor outcome in prostate cancer patients.Prostate tumors downregulate microseminoprotein-beta (MSMB) in the surrounding benign prostate epithelium and this response is associated with tumor aggressiveness.Prostate cancer induces C/EBPβ expression in surrounding epithelial cells which relates to tumor aggressiveness and patient outcome
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description
researcher ORCID ID = 0000-0003-3475-3230
@en
wetenschapper
@nl
name
Sofia Halin Bergström
@ast
Sofia Halin Bergström
@en
Sofia Halin Bergström
@nl
type
label
Sofia Halin Bergström
@ast
Sofia Halin Bergström
@en
Sofia Halin Bergström
@nl
prefLabel
Sofia Halin Bergström
@ast
Sofia Halin Bergström
@en
Sofia Halin Bergström
@nl
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P31
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0000-0003-3475-3230