about
Mutating RBF can enhance its pro-apoptotic activity and uncovers a new role in tissue homeostasis.Two different specific JNK activators are required to trigger apoptosis or compensatory proliferation in response to Rbf1 in Drosophila.Mitochondria, Bcl-2 family proteins and apoptosomes: of worms, flies and men.Apoptosis in Drosophila: which role for mitochondria?The pro-apoptotic activity of Drosophila Rbf1 involves dE2F2-dependent downregulation of diap1 and buffy mRNA.The Drosophila retinoblastoma protein induces apoptosis in proliferating but not in post-mitotic cells.Evolutionary conservation of Notch signaling inhibition by TMEM131L overexpression.The Drosophila retinoblastoma protein, Rbf1, induces a Debcl- and Drp1-dependent mitochondrial apoptosis.Production of dominant female sterility in Drosophila melanogaster by insertion of the ovoD1 allele on autosomes: use of transformed strains to generate germline mosaics.Bcl-2 and Bax mammalian regulators of apoptosis are functional in Drosophila.reaper and bax initiate two different apoptotic pathways affecting mitochondria and antagonized by bcl-2 in Drosophila.The myb-related gene stonewall induces both hyperplasia and cell death in Drosophila: rescue of fly lethality by coexpression of apoptosis inducers.The mitochondrial TOM complex modulates bax-induced apoptosis in Drosophila.The drosophila Bcl-2 family protein Debcl is targeted to the proteasome by the β-TrCP homologue slimb.[The comeback of mitochondria in Drosophila apoptosis]
P50
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P50
description
onderzoeker
@nl
researcher ORCID ID = 0000-0003-1186-1458
@en
name
Isabelle Guénal
@ast
Isabelle Guénal
@en
Isabelle Guénal
@es
Isabelle Guénal
@nl
type
label
Isabelle Guénal
@ast
Isabelle Guénal
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Isabelle Guénal
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Isabelle Guénal
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prefLabel
Isabelle Guénal
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Isabelle Guénal
@en
Isabelle Guénal
@es
Isabelle Guénal
@nl
P106
P1153
6602514300
P31
P496
0000-0003-1186-1458