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Global Phosphoproteomic Mapping of Early Mitotic Exit in Human Cells Identifies Novel Substrate Dephosphorylation MotifsTamoxifen-induced epigenetic silencing of oestrogen-regulated genes in anti-hormone resistant breast cancerGlobal characterization of signalling networks associated with tamoxifen resistance in breast cancer.Role of endoplasmic reticulum stress induction by the plant toxin, persin, in overcoming resistance to the apoptotic effects of tamoxifen in human breast cancer cells.Identification of PUMA as an estrogen target gene that mediates the apoptotic response to tamoxifen in human breast cancer cells and predicts patient outcome and tamoxifen responsiveness in breast cancer.Partial inhibition of Cdk1 in G 2 phase overrides the SAC and decouples mitotic events.BCL-2 hypermethylation is a potential biomarker of sensitivity to antimitotic chemotherapy in endocrine-resistant breast cancer.Transient tissue priming via ROCK inhibition uncouples pancreatic cancer progression, sensitivity to chemotherapy, and metastasis.Inhibition of activin signaling in lung adenocarcinoma increases the therapeutic index of platinum chemotherapy
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description
onderzoeker
@nl
researcher ORCID ID = 0000-0001-7791-4044
@en
name
Rachael A McCloy
@ast
Rachael A McCloy
@en
Rachael A McCloy
@es
Rachael A McCloy
@nl
type
label
Rachael A McCloy
@ast
Rachael A McCloy
@en
Rachael A McCloy
@es
Rachael A McCloy
@nl
prefLabel
Rachael A McCloy
@ast
Rachael A McCloy
@en
Rachael A McCloy
@es
Rachael A McCloy
@nl
P106
P1153
51261379700
P31
P496
0000-0001-7791-4044