about
Bi-directional transport of GABA in human embryonic kidney (HEK-293) cells stably expressing the rat GABA transporter GAT-1Two discontinuous segments in the carboxyl terminus are required for membrane targeting of the rat gamma-aminobutyric acid transporter-1 (GAT1)Oligomerization of the human serotonin transporter and of the rat GABA transporter 1 visualized by fluorescence resonance energy transfer microscopy in living cells.Molecular tools for GABAA receptors: High affinity ligands for β1-containing subtypes.The role of zinc ions in reverse transport mediated by monoamine transporters.Biochemical and functional properties of distinct nicotinic acetylcholine receptors in the superior cervical ganglion of mice with targeted deletions of nAChR subunit genes.Exploring the polyamine regulatory site of the NMDA receptor: a parallel synthesis approach.Ester to amide substitution improves selectivity, efficacy and kinetic behavior of a benzodiazepine positive modulator of GABAA receptors containing the α5 subunit.Nicotinic acetylcholine receptors control acetylcholine and noradrenaline release in the rodent habenulo-interpeduncular complexDual mode of stimulation by the beta-carboline ZK 91085 of recombinant GABA(A) receptor currents: molecular determinants affecting its actionCatecholamine outflow from mouse and rat brain slice preparations evoked by nicotinic acetylcholine receptor activation and electrical field stimulationNicotinic acetylcholine receptors modulate osteoclastogenesisUnexpected Properties of δ-Containing GABAA Receptors in Response to Ligands Interacting with the α+ β- Site.Serotonin-transporter mediated efflux: a pharmacological analysis of amphetamines and non-amphetamines.Substantial loss of substrate by diffusion during uptake in HEK-293 cells expressing neurotransmitter transporters.Characterization of carrier-mediated efflux in human embryonic kidney 293 cells stably expressing the rat serotonin transporter: a superfusion study.Extensive heterogeneity of recombinant gamma-aminobutyric acidA receptors expressed in alpha 4 beta 3 gamma 2-transfected human embryonic kidney 293 cells.Single-channel properties of α3β4, α3β4α5 and α3β4β2 nicotinic acetylcholine receptors in mice lacking specific nicotinic acetylcholine receptor subunits.Nicotinic acetylcholine receptor-subunit mRNAs in the mouse superior cervical ganglion are regulated by development but not by deletion of distinct subunit genes.Towards functional selectivity for α6β3γ2 GABAA receptors: a series of novel pyrazoloquinolinones.Role of α5-containing nicotinic receptors in neuropathic pain and response to nicotine.Investigation of neurotrophic factor concentrations with a novel in vitro concept for peripheral nerve regeneration.Engineered Flumazenil Recognition Site Provides Mechanistic Insight Governing Benzodiazepine Modulation in GABA ReceptorsA Human Polymorphism in CHRNA5 Is Linked to Relapse to Nicotine Seeking in Transgenic RatsDetection Methods for Autoantibodies in Suspected Autoimmune EncephalitisSAR-Guided Scoring Function and Mutational Validation Reveal the Binding Mode of CGS-8216 at the α1+/γ2– Benzodiazepine SiteThe role of the nAChR subunits α5, β2, and β4 on synaptic transmission in the mouse superior cervical ganglionDisturbed neurotransmitter homeostasis in ether lipid deficiency.Chronic exposure to manganese decreases striatal dopamine turnover in human alpha-synuclein transgenic miceDifferent Benzodiazepines Bind with Distinct Binding Modes to GABAA ReceptorsAttaining in vivo selectivity of positive modulation of α3βγ2 GABAA receptors in rats: A hard task!A novel de novo variant of GABRA1 causes increased sensitivity for GABA in vitroCoronaridine congeners potentiate GABAA receptors and induce sedative activity in mice in a benzodiazepine-insensitive mannerTrigeminal neuropathic pain development and maintenance in rats are suppressed by a positive modulator of α6 GABAA receptorsGABAA Receptor Ligands Often Interact with Binding Sites in the Transmembrane Domain and in the Extracellular Domain-Can the Promiscuity Code Be Cracked?Novel Benzodiazepine-Like Ligands with Various Anxiolytic, Antidepressant, or Pro-Cognitive ProfilesA photoswitchable GABA receptor channel blockerAmphetamines take two to tango: an oligomer-based counter-transport model of neurotransmitter transport explores the amphetamine action
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description
researcher ORCID ID = 0000-0003-4984-6034
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wetenschapper
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P Scholze
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P Scholze
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P Scholze
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P Scholze
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P Scholze
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P Scholze
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P Scholze
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P Scholze
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P Scholze
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P Scholze
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P Scholze
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P Scholze
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P106
P1153
6603948130
P31
P496
0000-0003-4984-6034