about
Study of a mechanism responsible for potential antidepressant activity of EMD 386088, a 5-HT6 partial agonist in ratsAntidepressant- and Anxiolytic-Like Effects of New Dual 5-HT₁A and 5-HT₇ Antagonists in Animal ModelsTowards new 5-HT7 antagonists among arylsulfonamide derivatives of (aryloxy)ethyl-alkyl amines: Multiobjective based design, synthesis, and antidepressant and anxiolytic properties.N1-Azinylsulfonyl-1H-indoles: 5-HT6 Receptor Antagonists with Procognitive and Antidepressant-Like PropertiesADN-1184, a monoaminergic ligand with 5-HT6/7 receptor antagonist action, exhibits activity in animal models of anxiety.Behavioral pharmacology: potential antidepressant and anxiolytic properties.Antidepressant-like activity of EMD 386088, a 5-HT6 receptor partial agonist, following systemic acute and chronic administration to rats.Metabolic and Cardiovascular Benefits and Risks of EMD386088-A 5-HT6 Receptor Partial Agonist and Dopamine Transporter Inhibitor.Anxiolytic-like activity of zinc in rodent tests.Antidepressant and antipsychotic activity of new quinoline- and isoquinoline-sulfonamide analogs of aripiprazole targeting serotonin 5-HT₁A/5-HT₂A/5-HT₇ and dopamine D₂/D₃ receptors.Partial agonist efficacy of EMD386088, a 5-HT6 receptor ligand, in functional in vitro assays.Synthesis and pharmacological evaluation of novel tricyclic[2,1-f]theophylline derivatives.Pharmacological evaluation of the anxiolytic-like effects of EMD 386088, a partial 5-HT6 receptor agonist, in the rat elevated plus-maze and Vogel conflict tests.Activity of Serotonin 5-HT1A Receptor Biased Agonists in Rat: Anxiolytic and Antidepressant-like properties.Novel 3-(1,2,3,6-Tetrahydropyridin-4-yl)-1H-indole-Based Multifunctional Ligands with Antipsychotic-Like, Mood-Modulating, and Procognitive Activity.In the search for a lead structure among series of potent and selective hydantoin 5-HT7 R agents: The drug-likeness in vitro study.The impact of the halogen bonding on D2 and 5-HT1A/5-HT7 receptor activity of azinesulfonamides of 4-[(2-ethyl)piperidinyl-1-yl]phenylpiperazines with antipsychotic and antidepressant properties.Novel 5-HT7R antagonists, arylsulfonamide derivatives of (aryloxy)propyl piperidines: Add-on effect to the antidepressant activity of SSRI and DRI, and pro-cognitive profile.Study on the effect of EMD386088, a 5-HT6 receptor partial agonist, in enhancing the anti-immobility action of some antidepressants in rats.N-Alkylated arylsulfonamides of (aryloxy)ethyl piperidines: 5-HT(7) receptor selectivity versus multireceptor profile.Antidepressant- and anxiolytic-like activity of 7-phenylpiperazinylalkyl-1,3-dimethyl-purine-2,6-dione derivatives with diversified 5-HT₁A receptor functional profile.Tail suspension test does not detect antidepressant-like properties of atypical antipsychotics.MF-8, a novel promising arylpiperazine-hydantoin based 5-HT7 receptor antagonist: In vitro drug-likeness studies and in vivo pharmacological evaluation.Computer-aided insights into receptor-ligand interaction for novel 5-arylhydantoin derivatives as serotonin 5-HT7 receptor agents with antidepressant activity.Novel tricyclic[2,1-f]theophylline derivatives of LCAP with activity in mouse models of affective disorders.The computer-aided discovery of novel family of the 5-HT6 serotonin receptor ligands among derivatives of 4-benzyl-1,3,5-triazine.Synthesis and biological investigation of new equatorial (β) stereoisomers of 3-aminotropane arylamides with atypical antipsychotic profile.Computer-Aided Studies for Novel Arylhydantoin 1,3,5-Triazine Derivatives as 5-HT₆ Serotonin Receptor Ligands with Antidepressive-Like, Anxiolytic and Antiobesity Action In VivoChronic antidepressant-like effect of EMD386088, a partial 5-HT receptor agonist, in olfactory bulbectomy model may be connected with BDNF and/or CREB signalling pathwayNovel antagonists of 5-HT and/or 5-HT receptors affect the brain monoamines metabolism and enhance the anti-immobility activity of different antidepressants in ratsArene- and quinoline-sulfonamides as novel 5-HT7 receptor ligandsQuinoline- and isoquinoline-sulfonamide derivatives of LCAP as potent CNS multi-receptor-5-HT1A/5-HT2A/5-HT7 and D2/D3/D4-agents: the synthesis and pharmacological evaluationSynthesis and SAR-study for novel arylpiperazine derivatives of 5-arylidenehydantoin with α₁-adrenoceptor antagonistic propertiesDerivatives of pyrrolo[3,4-d]pyridazinone, a new class of analgesic agentsArylpiperazinylalkyl derivatives of 8-amino-1,3-dimethylpurine-2,6-dione as novel multitarget 5-HT/D receptor agents with potential antipsychotic activityThe preclinical discovery and development of cariprazine for the treatment of schizophreniaSynthesis and biological investigations of 3β-aminotropane arylamide derivatives with atypical antipsychotic profileNovel Aryloxyethyl Derivatives of 1-(1-Benzoylpiperidin-4-yl)methanamine as the Extracellular Regulated Kinases 1/2 (ERK1/2) Phosphorylation-Preferring Serotonin 5-HT1A Receptor-Biased Agonists with Robust Antidepressant-like ActivityAre the Hydantoin-1,3,5-triazine 5-HT6R Ligands a Hope to a Find New Procognitive and Anti-Obesity Drug? Considerations Based on Primary In Vivo Assays and ADME-Tox Profile In VitroThe 1,3,5-Triazine Derivatives as Innovative Chemical Family of 5-HT6 Serotonin Receptor Agents with Therapeutic Perspectives for Cognitive Impairment
P50
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P50
description
Polish researcher
@en
Pools onderzoekster
@nl
polski naukowiec
@pl
taighdeoir Polannach
@ga
name
Magdalena Jastrzębska-Więsek
@ast
Magdalena Jastrzębska-Więsek
@ca
Magdalena Jastrzębska-Więsek
@cs
Magdalena Jastrzębska-Więsek
@de
Magdalena Jastrzębska-Więsek
@en
Magdalena Jastrzębska-Więsek
@es
Magdalena Jastrzębska-Więsek
@fr
Magdalena Jastrzębska-Więsek
@ga
Magdalena Jastrzębska-Więsek
@gl
Magdalena Jastrzębska-Więsek
@hr
type
label
Magdalena Jastrzębska-Więsek
@ast
Magdalena Jastrzębska-Więsek
@ca
Magdalena Jastrzębska-Więsek
@cs
Magdalena Jastrzębska-Więsek
@de
Magdalena Jastrzębska-Więsek
@en
Magdalena Jastrzębska-Więsek
@es
Magdalena Jastrzębska-Więsek
@fr
Magdalena Jastrzębska-Więsek
@ga
Magdalena Jastrzębska-Więsek
@gl
Magdalena Jastrzębska-Więsek
@hr
altLabel
Magdalena Jastrzebska-Wiesek
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prefLabel
Magdalena Jastrzębska-Więsek
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Magdalena Jastrzębska-Więsek
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Magdalena Jastrzębska-Więsek
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Magdalena Jastrzębska-Więsek
@de
Magdalena Jastrzębska-Więsek
@en
Magdalena Jastrzębska-Więsek
@es
Magdalena Jastrzębska-Więsek
@fr
Magdalena Jastrzębska-Więsek
@ga
Magdalena Jastrzębska-Więsek
@gl
Magdalena Jastrzębska-Więsek
@hr
P106
P1153
8429460600
P1412
P1559
Magdalena Jastrzębska-Więsek
@pl
P21
P214
2348147425852845040003
P27
P31
P3124
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0000-0002-5388-1214
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P7859
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