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MED1: a central molecule for maintenance of genome integrity and response to DNA damageMany different tumor types have polyclonal tumor origin: evidence and implications.Breast Cancer Heterogeneity Examined by High-Sensitivity Quantification of PIK3CA, KRAS, HRAS, and BRAF Mutations in Normal Breast and Ductal CarcinomasLow-frequency KRAS mutations are prevalent in lung adenocarcinomasKRAS mutant tumor subpopulations can subvert durable responses to personalized cancer treatmentsOncomutations as biomarkers of cancer risk.Hotspot oncomutations: implications for personalized cancer treatment.Variation in organ-specific PIK3CA and KRAS mutant levels in normal human tissues correlates with mutation prevalence in corresponding carcinomas.Dose and temporal evaluation of ethylene oxide-induced mutagenicity in the lungs of male big blue mice following inhalation exposure to carcinogenic concentrations.K-RAS mutation in the screening, prognosis and treatment of cancer.Quantification of Kras mutant fraction in the lung DNA of mice exposed to aerosolized particulate vanadium pentoxide by inhalation.Pms2 deficiency results in increased mutation in the Hprt gene but not the Tk gene of Tk(+/-) transgenic mice.Tandemly repeated sequences are present at the ends of the DNA of raccoonpox virus.Temporal changes in K-ras mutant fraction in lung tissue of big blue B6C3F₁ mice exposed to ethylene oxide.Aristolochic acid-induced carcinogenesis examined by ACB-PCR quantification of H-Ras and K-Ras mutant fraction.Accumulation of K-Ras codon 12 mutations in the F344 rat distal colon following azoxymethane exposure.Measurement of tumor-associated mutations in the nasal mucosa of rats exposed to varying doses of formaldehyde.K-Ras mutant fraction in A/J mouse lung increases as a function of benzo[a]pyrene dose.Occurrence of H-ras codon 61 CAA to AAA mutation during mouse liver tumor progression.ACB-PCR measurement of spontaneous and furan-induced H-ras codon 61 CAA to CTA and CAA to AAA mutation in B6C3F1 mouse liver.Quantifying levels of p53 mutation in mouse skin tumors.Levels of 4-aminobiphenyl-induced somatic H-ras mutation in mouse liver DNA correlate with potential for liver tumor development.Ovarian effects of prenatal exposure to benzo[a]pyrene: Roles of embryonic and maternal glutathione status.4-Aminobiphenyl induces liver DNA adducts in both neonatal and adult mice but induces liver mutations only in neonatal mice.Levels of H-ras codon 61 CAA to AAA mutation: response to 4-ABP-treatment and Pms2-deficiency.The 40th anniversary of the Environmental Mutagen Society.ACB-PCR measurement of H-ras codon 61 CAA→CTA mutation provides an early indication of aristolochic acid I carcinogenic effect in tumor target tissues.p53 codon 271 CGT to CAT mutant fraction does not increase in nasal respiratory and olfactory epithelia of rats exposed to inhaled naphthalene.Assessment of K-Ras mutant frequency and micronucleus incidence in the mouse duodenum following 90-days of exposure to Cr(VI) in drinking water.Simulated solar light-induced p53 mutagenesis in SKH-1 mouse skin: a dose-response assessment.Fixation and Spread of Somatic Mutations in Adult Human Colonic Epithelium.Lifespan Kras mutation levels in lung and liver of B6C3F miceAccumulation of wound-inducible ACC synthase transcript in tomato fruit is inhibited by salicylic acid and polyaminesDetection of rare K-ras codon 12 mutations using allele-specific competitive blocker PCRDetection of basepair substitution mutation at a frequency of 1 x 10(-7) by combining two genotypic selection methods, MutEx enrichment and allele-specific competitive blocker PCRDetection of a mouse H-ras codon 61 mutation using a modified allele-specific competitive blocker PCR genotypic selection methodA subset of papillary thyroid carcinomas contain KRAS mutant subpopulations at levels above normal thyroidACB-PCR quantification of somatic oncomutationMulticlonal tumor origin: Evidence and implications
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description
onderzoeker
@nl
researcher ORCID ID = 0000-0002-3005-2552
@en
name
Barbara L Parsons
@ast
Barbara L Parsons
@en
Barbara L Parsons
@es
Barbara L Parsons
@nl
type
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Barbara L Parsons
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Barbara L Parsons
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Barbara L Parsons
@es
Barbara L Parsons
@nl
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Barbara Parsons
@en
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Barbara L Parsons
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Barbara L Parsons
@en
Barbara L Parsons
@es
Barbara L Parsons
@nl
P106
P1153
7101948948
P21
P31
P496
0000-0002-3005-2552