about
Collybolide is a novel biased agonist of κ-opioid receptors with potent antipruritic activityDrug dependent sex-differences in periaqueducatal gray mediated antinociception in the ratContribution of adenylyl cyclase modulation of pre- and postsynaptic GABA neurotransmission to morphine antinociception and tolerance.Change in functional selectivity of morphine with the development of antinociceptive tolerance.Opioid receptor internalization contributes to dermorphin-mediated antinociceptionIdentification of a small-molecule ligand that activates the neuropeptide receptor GPR171 and increases food intake.The BigLEN-GPR171 Peptide Receptor System Within the Basolateral Amygdala Regulates Anxiety-Like Behavior and Contextual Fear Conditioning.Ligand-biased activation of extracellular signal-regulated kinase 1/2 leads to differences in opioid induced antinociception and tolerance.Glutamate modulation of antinociception, but not tolerance, produced by morphine microinjection into the periaqueductal gray of the rat.Identification of GPR83 as the receptor for the neuroendocrine peptide PEN.Endothelin-converting enzyme 2 differentially regulates opioid receptor activity.Enhanced antinociception with repeated microinjections of apomorphine into the periaqueductal gray of male and female rats.Opioid-Induced Signaling and Antinociception Are Modulated by the Recently Deorphanized Receptor, GPR171
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description
researcher ORCID ID = 0000-0001-8421-883X
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wetenschapper
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E Bobeck
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33467576900
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0000-0001-8421-883X