about
Endocytic Ark/Prk kinases play a critical role in adriamycin resistance in both yeast and mammalian cells.A novel role for Bsd2 in the resistance of yeast to adriamycin.siRNA-mediated inhibition of phosphatidylinositol glycan Class B (PIGB) confers resistance to methylmercury in HEK293 cells.Overexpression of Ycg1 or Ydr520c confers resistance to cadmium in Saccharomyces cerevisiae.The protein transportation pathway from Golgi to vacuoles via endosomes plays a role in enhancement of methylmercury toxicity.Comparative photodynamic therapy cytotoxicity of mannose-conjugated chlorin and talaporfin sodium in cultured human and rat cells.Transport of pyruvate into mitochondria is involved in methylmercury toxicity.Methylmercury induces the expression of TNF-α selectively in the brain of mice.Increased production of reactive oxygen species by the vacuolar-type (H(+))-ATPase inhibitors bafilomycin A1 and concanamycin A in RAW 264 cells.Galacto-N-biose is neuroprotective against glutamate-induced excitotoxicity in vitro.Functions of yeast helicase Ssl2p that are essential for viability are also involved in protection from the toxicity of adriamycin.FBXO6 attenuates cadmium toxicity in HEK293 cells by inhibiting ER stress and JNK activation.Global chemokine expression in methylmercury-treated mice: methylmercury induces brain-specific expression of CCL3 and CCL4.Knockdown of the gene for homeobox protein HOXB13 reduces toxicity of oxidative-stress inducers in HEK293 cells.Inhibition of F-box protein FBXO6 gene expression by RNA interference enhances cadmium toxicity in HEK293 cells.siRNA-mediated AMPKalpha1 subunit gene PRKAA1 silencing enhances methylmercury toxicity in HEK293 cells.Dysfunctional nascent polypeptide-associated complex (NAC) activity in ribosomes enhances adriamycin toxicity in budding yeast.Brain-specific induction of secretoglobin 3A1 expression in mice treated with methylmercury.Changes in the levels of low molecular weight metabolites in the mouse cerebellum following treatment with methylmercury.Synthesis, antitumor activity, and cytotoxicity of 4-substituted 1-benzyl-5-diphenylstibano-1H-1,2,3-triazoles.Whi2 enhances methylmercury toxicity in yeast via inhibition of Akr1 palmitoyltransferase activity.[A screen for genes involved in adriamycin resistance in Saccharomyces cerevisiae].Photodynamic therapy using talaporfin sodium induces heme oxygenase-1 expression in rat malignant meningioma KMY-J cells.Effect of Metallothionein-III on Mercury-Induced Chemokine Gene ExpressionOverexpression of CLN1, CLN2, or ERG13 increases resistance to adriamycin in Saccharomyces cerevisiae.siRNA-mediated silencing of the gene for heat shock transcription factor 1 causes hypersensitivity to methylmercury in HEK293 cellsSilencing of the gene for homeobox protein HOXB13 by siRNA confers resistance to methylmercury on HEK293 cellssiRNA-mediated knockdown of the melanocortin 2 receptor accessory protein 2 (MRAP2) gene confers resistance to methylmercury on HEK293 cells[Studies on molecular mechanism of toxicity of anticancer drugs]Gene expression profiling using DNA microarray analysis of the cerebellum of mice treated with methylmercuryMethylmercury induces CCL2 expression through activation of NF-κB in human 1321N1 astrocytesUbiquitin-conjugating enzyme Cdc34 mediates methylmercury resistance in Saccharomyces cerevisiae by increasing Whi2 degradationIdentification of deubiquitinating enzymes involved in methylmercury toxicity in Saccharomyces cerevisiaeDeletion of the ubiquitin-conjugating enzyme Ubc2 confers resistance to methylmercury in budding yeast by promoting Whi2 degradationChemokine CCL4 Induced in Mouse Brain Has a Protective Role against Methylmercury Toxicity
P50
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P50
description
researcher ORCID ID = 0000-0003-4723-9513
@en
name
Tsutomu Takahashi
@ast
Tsutomu Takahashi
@en
Tsutomu Takahashi
@es
Tsutomu Takahashi
@nl
type
label
Tsutomu Takahashi
@ast
Tsutomu Takahashi
@en
Tsutomu Takahashi
@es
Tsutomu Takahashi
@nl
prefLabel
Tsutomu Takahashi
@ast
Tsutomu Takahashi
@en
Tsutomu Takahashi
@es
Tsutomu Takahashi
@nl
P1153
55520650900
P31
P496
0000-0003-4723-9513