about
Alkyne-substituted diminazene as G-quadruplex binders with anticancer activities.Temperature and osmotic stress dependence of the thermodynamics for binding linker histone H10, Its carboxyl domain (H10-C) or globular domain (H10-G) to B-DNA.Suramin potently inhibits cGAMP synthase, cGAS, in THP1 cells to modulate IFN-β levels.Berenil Binds Tightly to Parallel and Mixed Parallel/Antiparallel G-Quadruplex Motifs with Varied Thermodynamic SignaturesDiminazene or berenil, a classic duplex minor groove binder, binds to G-quadruplexes with low nanomolar dissociation constants and the amidine groups are also critical for G-quadruplex bindingPotently inhibiting cancer cell migration with novel 3H-pyrazolo[4,3-f]quinoline boronic acid ROCK inhibitors
P50
description
Forscher
@de
chercheur
@fr
investigador
@es
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
研究者
@zh
name
Clinton G Mikek
@ast
Clinton G Mikek
@en
Clinton G Mikek
@es
Clinton G Mikek
@nl
type
label
Clinton G Mikek
@ast
Clinton G Mikek
@en
Clinton G Mikek
@es
Clinton G Mikek
@nl
prefLabel
Clinton G Mikek
@ast
Clinton G Mikek
@en
Clinton G Mikek
@es
Clinton G Mikek
@nl
P31
P496
0000-0001-5662-3096