about
Human immunodeficiency virus type 1 Tat increases the expression of cleavage and polyadenylation specificity factor 73-kilodalton subunit modulating cellular and viral expressionMechanisms of HIV-1 inhibition by the lipid mediator N-arachidonoyldopamineBag1-L is a phosphorylation-dependent coactivator of c-Jun during neuronal apoptosis.Anti-Tat and anti-HIV activities of trimers of n-alkylglycines.Loss of Fbw7 reprograms adult pancreatic ductal cells into α, δ, and β cells.4-Phenylcoumarins as HIV transcription inhibitors.Fbw7 repression by hes5 creates a feedback loop that modulates Notch-mediated intestinal and neural stem cell fate decisions.Stem cell and progenitor fate in the mammalian intestine: Notch and lateral inhibition in homeostasis and disease.Fbw7 and its counteracting forces in stem cells and cancer: Oncoproteins in the balance.3-Phenylcoumarins as inhibitors of HIV-1 replication.c-Jun N-terminal phosphorylation antagonises recruitment of the Mbd3/NuRD repressor complex.In vitro anti-HIV-1 properties of ethnobotanically selected South African plants used in the treatment of sexually transmitted diseases.Basiliolides, a class of tetracyclic C19 dilactones from Thapsia garganica, release Ca(2+) from the endoplasmic reticulum and regulate the activity of the transcription factors nuclear factor of activated T cells, nuclear factor-kappaB, and activatoNeoflavonoids as Inhibitors of HIV-1 Replication by Targeting the Tat and NF-κB Pathways.Imperatorin inhibits HIV-1 replication through an Sp1-dependent pathway.The CB1/VR1 agonist arvanil induces apoptosis through an FADD/caspase-8-dependent pathway.Non-pungent capsaicinoids from sweet pepper synthesis and evaluation of the chemopreventive and anticancer potential.Anandamide inhibits nuclear factor-kappaB activation through a cannabinoid receptor-independent pathway.ATMIN is required for maintenance of genomic stability and suppression of B cell lymphoma.JNK signalling modulates intestinal homeostasis and tumourigenesis in mice.Immunosuppressive activity of capsaicinoids: capsiate derived from sweet peppers inhibits NF-kappaB activation and is a potent antiinflammatory compound in vivo.Involvement of reactive oxygen species in capsaicinoid-induced apoptosis in transformed cells.Caffeic acid phenethyl ester inhibits T-cell activation by targeting both nuclear factor of activated T-cells and NF-kappaB transcription factors.Anti-HIV activity of some synthetic lignanolides and intermediates.Imperatorin inhibits T-cell proliferation by targeting the transcription factor NFAT.Mesuol, a natural occurring 4-phenylcoumarin, inhibits HIV-1 replication by targeting the NF-kappaB pathway.Duct- and Acinar-Derived Pancreatic Ductal Adenocarcinomas Show Distinct Tumor Progression and Marker Expression.The acetaminophen-derived bioactive N-acylphenolamine AM404 inhibits NFAT by targeting nuclear regulatory events.The F-box protein Fbw7 is required for cerebellar development.Phenotypic plasticity in the pancreas: new triggers, new players.F-box and WD repeat domain-containing 7 regulates intestinal cell lineage commitment and is a haploinsufficient tumor suppressor.Stress-inducible-stem cells: a new view on endocrine, metabolic and mental disease?LUBAC determines chemotherapy resistance in squamous cell lung cancerAn aqueous stem bark extract of Mangifera indica (Vimang) inhibits T cell proliferation and TNF-induced activation of nuclear transcription factor NF-kappaBVanilloid receptor-1 regulates neurogenic inflammation in colon and protects mice from colon cancerAnti-HIV activity of stilbene-related heterocyclic compoundsSingle cell analysis of human foetal liver captures the transcriptional profile of hepatobiliary hybrid progenitors
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