about
Effects of serotonin in the hippocampus: how SSRIs and multimodal antidepressants might regulate pyramidal cell functionA critical evaluation of the activity-regulated cytoskeleton-associated protein (Arc/Arg3.1)'s putative role in regulating dendritic plasticity, cognitive processes, and mood in animal models of depressionAltered γ-aminobutyric acid neurotransmission in major depressive disorder: a critical review of the supporting evidence and the influence of serotonergic antidepressantsSerotonin receptor mechanisms mediate the discriminative stimulus properties of the atypical antipsychotic clozapine in C57BL/6 mice.Brexpiprazole I: in vitro and in vivo characterization of a novel serotonin-dopamine activity modulator.Multimodal antidepressant vortioxetine increases frontal cortical oscillations unlike escitalopram and duloxetine--a quantitative EEG study in rats.Pharmacological effects of Lu AA21004: a novel multimodal compound for the treatment of major depressive disorder.Lu AA21004, a novel multimodal antidepressant, produces regionally selective increases of multiple neurotransmitters--a rat microdialysis and electrophysiology study.The rapid recovery of 5-HT cell firing induced by the antidepressant vortioxetine involves 5-HT(3) receptor antagonism.Vortioxetine, but not escitalopram or duloxetine, reverses memory impairment induced by central 5-HT depletion in rats: evidence for direct 5-HT receptor modulation.Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 2, pharmacological interactions in rodents suggest a role of serotonin-3 receptor antagonism.The interaction of escitalopram and R-citalopram at the human serotonin transporter investigated in the mouse.The influence of NMDA and GABA(A) receptors and glutamic acid decarboxylase (GAD) activity on attentionAcute nicotine reduces and repeated nicotine increases spontaneous activity in male and female Lewis rats.Treatment of cognitive dysfunction in major depressive disorder--a review of the preclinical evidence for efficacy of selective serotonin reuptake inhibitors, serotonin-norepinephrine reuptake inhibitors and the multimodal-acting antidepressant vortSerotonergic Regulation of Prefrontal Cortical Circuitries Involved in Cognitive Processing: A Review of Individual 5-HT Receptor Mechanisms and Concerted Effects of 5-HT Receptors Exemplified by the Multimodal Antidepressant Vortioxetine.Regional distribution of serotonergic receptors: a systems neuroscience perspective on the downstream effects of the multimodal-acting antidepressant vortioxetine on excitatory and inhibitory neurotransmission.Histamine may contribute to vortioxetine's procognitive effects; possibly through an orexigenic mechanism.Task- and Treatment Length-Dependent Effects of Vortioxetine on Scopolamine-Induced Cognitive Dysfunction and Hippocampal Extracellular Acetylcholine in Rats.Neuroplasticity pathways and protein-interaction networks are modulated by vortioxetine in rodents.Effect of the multimodal acting antidepressant vortioxetine on rat hippocampal plasticity and recognition memory.Vortioxetine restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats.Generalization to atypical antipsychotic drugs depends on training dose in rats trained to discriminate 1.25 mg/kg clozapine versus 5.0 mg/kg clozapine versus vehicle in a three-choice drug discrimination task.The effects of acute and repeated nicotine doses on spontaneous activity in male and female Sprague Dawley rats: analysis of brain area epibatidine binding and cotinine levels.The antidepressant drugs fluoxetine and duloxetine produce anxiolytic-like effects in a schedule-induced polydipsia paradigm in rats: enhancement of fluoxetine's effects by the α2 adrenoceptor antagonist yohimbine.Discriminative stimulus properties of 1.25mg/kg clozapine in rats: Mediation by serotonin 5-HT2 and dopamine D4 receptors.Discriminative stimulus properties of the atypical antipsychotic drug clozapine in rats trained to discriminate 1.25 mg/kg clozapine vs. 5.0 mg/kg clozapine vs. vehicle.A study of time- and sex-dependent effects of vortioxetine on rat sexual behavior: Possible roles of direct receptor modulation.Serotonin Transporter-Independent Actions of the Antidepressant Vortioxetine As Revealed Using the SERT Met172 Mouse.Reversal of age-associated cognitive deficits is accompanied by increased plasticity-related gene expression after chronic antidepressant administration in middle-aged mice.A 5-HT3 receptor antagonist potentiates the behavioral, neurochemical and electrophysiological actions of an SSRI antidepressant.Chronic vortioxetine treatment in rodents modulates gene expression of neurodevelopmental and plasticity markers.In vivo and in vitro effects of vortioxetine on molecules associated with neuroplasticity.
P50
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P50
description
researcher ORCID ID = 0000-0002-0470-0202
@en
name
Alan L Pehrson
@ast
Alan L Pehrson
@en
Alan L Pehrson
@es
Alan L Pehrson
@nl
type
label
Alan L Pehrson
@ast
Alan L Pehrson
@en
Alan L Pehrson
@es
Alan L Pehrson
@nl
prefLabel
Alan L Pehrson
@ast
Alan L Pehrson
@en
Alan L Pehrson
@es
Alan L Pehrson
@nl
P1153
8583055000
P31
P496
0000-0002-0470-0202