about
SIRT1 is a redox-sensitive deacetylase that is post-translationally modified by oxidants and carbonyl stressTargeted disruption of NF-{kappa}B1 (p50) augments cigarette smoke-induced lung inflammation and emphysema in mice: a critical role of p50 in chromatin remodelingAnti-inflammatory effect of a selective IkappaB kinase-beta inhibitor in rat lung in response to LPS and cigarette smoke.Resveratrol induces glutathione synthesis by activation of Nrf2 and protects against cigarette smoke-mediated oxidative stress in human lung epithelial cells.FOXO3 deficiency leads to increased susceptibility to cigarette smoke-induced inflammation, airspace enlargement, and chronic obstructive pulmonary diseaseSIRT1, an antiinflammatory and antiaging protein, is decreased in lungs of patients with chronic obstructive pulmonary disease.Redox regulation of lung inflammation: role of NADPH oxidase and NF-kappaB signalling.Deacetylases and NF-kappaB in redox regulation of cigarette smoke-induced lung inflammation: epigenetics in pathogenesis of COPD.Disruption of p21 attenuates lung inflammation induced by cigarette smoke, LPS, and fMLP in mice.Curcumin restores corticosteroid function in monocytes exposed to oxidants by maintaining HDAC2Cigarette smoke-mediated inflammatory and oxidative responses are strain-dependent in mice.
P50
Q33553021-1EE969ED-123D-4B41-BE44-D3587AC49A1CQ33655868-226265BD-40FA-43B3-8D9F-81C999366B2FQ33774669-F95CAC07-ED22-4FAA-B6C4-994838E05310Q34731017-89BC169B-7397-4338-9061-F72CB0E094B2Q35091274-14DD4E6E-B1E7-4D43-BCDD-A5901BBC2283Q36539471-84D0DBD3-97A5-4B2B-91B9-64928E9D3A96Q36979666-98AC3A89-D2C0-4A01-AD89-E9D237BD2411Q37065224-95A6C91D-F4F4-439E-AC78-FF8CB1906700Q39587342-CBD0FDE3-67B4-46F4-B592-44DBB50CC26CQ42683435-E4335B9B-8301-4F7F-8A32-3F36C4FABC3EQ46674627-930A07D3-FD0A-4DE1-B5F6-A1F4CD981452
P50
description
researcher ORCID ID = 0000-0002-4234-9417
@en
name
Saravanan Rajendrasozhan
@ast
Saravanan Rajendrasozhan
@en
Saravanan Rajendrasozhan
@es
Saravanan Rajendrasozhan
@nl
type
label
Saravanan Rajendrasozhan
@ast
Saravanan Rajendrasozhan
@en
Saravanan Rajendrasozhan
@es
Saravanan Rajendrasozhan
@nl
prefLabel
Saravanan Rajendrasozhan
@ast
Saravanan Rajendrasozhan
@en
Saravanan Rajendrasozhan
@es
Saravanan Rajendrasozhan
@nl
P31
P496
0000-0002-4234-9417