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Comprehensive mapping of HLA-A0201-restricted CD8 T-cell epitopes on PDC-E2 in primary biliary cirrhosisDeficiency in regulatory T cells results in development of antimitochondrial antibodies and autoimmune cholangitis.Prss16 is not required for T-cell development.B-cell depletion with anti-CD20 ameliorates autoimmune cholangitis but exacerbates colitis in transforming growth factor-beta receptor II dominant negative miceDifferential modulation by IL-17A of Cholangitis versus Colitis in IL-2Rα deleted mice.Deletion of interleukin-6 in mice with the dominant negative form of transforming growth factor beta receptor II improves colitis but exacerbates autoimmune cholangitisLymphoma-like T cell infiltration in liver is associated with increased copy number of dominant negative form of TGFβ receptor II.Respiratory influenza virus infection induces intestinal immune injury via microbiota-mediated Th17 cell-dependent inflammationB cells promote hepatic inflammation, biliary cyst formation, and salivary gland inflammation in the NOD.c3c4 model of autoimmune cholangitis.Fine phenotypic and functional characterization of effector cluster of differentiation 8 positive T cells in human patients with primary biliary cirrhosisHepatic IL-17 responses in human and murine primary biliary cirrhosisComparative analysis of portal cell infiltrates in antimitochondrial autoantibody-positive versus antimitochondrial autoantibody-negative primary biliary cirrhosisForkhead Box O1 Regulates Macrophage Polarization Following Staphylococcus aureus Infection: Experimental Murine Data and Review of the Literature.The immunobiology of colitis and cholangitis in interleukin-23p19 and interleukin-17A deleted dominant negative form of transforming growth factor beta receptor type II miceDeletion of interleukin (IL)-12p35 induces liver fibrosis in dominant-negative TGFβ receptor type II mice.Regulatory T cells: development, function and role in autoimmunity.Identification of HLA-A2-restricted CD8(+) cytotoxic T cell responses in primary biliary cirrhosis: T cell activation is augmented by immune complexes cross-presented by dendritic cells.Increased frequency of pre-pro B cells in the bone marrow of New Zealand Black (NZB) mice: implications for a developmental block in B cell differentiation.B cells and autoimmune liver diseases.Overexpression of microRNA-21 is associated with elevated pro-inflammatory cytokines in dominant-negative TGF-β receptor type II mouse.Successful treatment of murine autoimmune cholangitis by parabiosis: Implications for hematopoietic therapySystems biologic analysis of T regulatory cells genetic pathways in murine primary biliary cirrhosis.Appearance of human plasma cells following differentiation of human B cells in NOD/SCID mouse spleen.The current immune function of hepatic dendritic cells.Clonality, activated antigen-specific CD8(+) T cells, and development of autoimmune cholangitis in dnTGFβRII miceDifferential mechanisms in the pathogenesis of autoimmune cholangitis versus inflammatory bowel disease in interleukin-2Ralpha(-/-) miceLoss of tolerance in C57BL/6 mice to the autoantigen E2 subunit of pyruvate dehydrogenase by a xenobiotic with ensuing biliary ductular disease.CD8 T cells mediate direct biliary ductule damage in nonobese diabetic autoimmune biliary disease.Dysregulation of peritoneal cavity B1a cells and murine primary biliary cholangitis.Adoptive transfer of CD8(+) T cells from transforming growth factor beta receptor type II (dominant negative form) induces autoimmune cholangitis in mice.Diverse roles of invariant natural killer T cells in liver injury and fibrosis induced by carbon tetrachloride.Sorafenib inhibits macrophage-mediated epithelial-mesenchymal transition in hepatocellular carcinoma.Deletion of interleukin-12p40 suppresses autoimmune cholangitis in dominant negative transforming growth factor beta receptor type II mice.Myeloid STAT3 inhibits T cell-mediated hepatitis by regulating T helper 1 cytokine and interleukin-17 production.Block of both TGF-β and IL-2 signaling impedes Neurophilin-1+ regulatory T cell and follicular regulatory T cell development.Traditional Chinese medicine and immune regulation.The intestinal microbiota and microenvironment in liver.Expansion of bone marrow IFN-alpha-producing dendritic cells in New Zealand Black (NZB) mice: high level expression of TLR9 and secretion of IFN-alpha in NZB bone marrow.Epigenetics and Primary Biliary Cirrhosis: a Comprehensive Review and Implications for Autoimmunity.Development of autoantibodies precedes clinical manifestations of autoimmune diseases: A comprehensive review.
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description
researcher ORCID ID = 0000-0002-9525-1421
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wetenschapper
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name
Zhe-Xiong Lian
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Zhe-Xiong Lian
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Zhe-Xiong Lian
@es
Zhe-Xiong Lian
@nl
type
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Zhe-Xiong Lian
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Zhe-Xiong Lian
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Zhe-Xiong Lian
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Zhe-Xiong Lian
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prefLabel
Zhe-Xiong Lian
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Zhe-Xiong Lian
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Zhe-Xiong Lian
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Zhe-Xiong Lian
@nl
P31
P496
0000-0002-9525-1421