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The role of BH3-only proteins in apoptosis within the ovaryHow Is the Number of Primordial Follicles in the Ovarian Reserve Established?The environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin disrupts morphogenesis of the rat pre-implantation embryo.The environmental toxicant 2,3,7,8-tetrachlorodibenzo-p-dioxin disturbs the establishment and maintenance of cell polarity in preimplantation rat embryos.Clinical applications and limitations of current ovarian stem cell research: a reviewMolecular correlates of platinum response in human high-grade serous ovarian cancer patient-derived xenograftsDNA damage-induced primordial follicle oocyte apoptosis and loss of fertility require TAp63-mediated induction of Puma and NoxaApoptosis in the germ line.Taking control of the female fertile lifespan: a key role for Bcl-2 family proteins.BCL2-modifying factor promotes germ cell loss during murine oogenesis.The ovarian reserve is depleted during puberty in a hormonally driven process dependent on the pro-apoptotic protein BMFCisplatin-induced primordial follicle oocyte killing and loss of fertility are not prevented by imatinib.Dual roles for Id4 in the regulation of estrogen signaling in the mammary gland and ovary.How to best preserve oocytes in female cancer patients exposed to DNA damage inducing therapeutics.The importance of DNA repair for maintaining oocyte quality in response to anti-cancer treatments, environmental toxins and maternal ageing.Meiotic spindle dynamics in human oocytes following slow-cooling cryopreservation.Loss of the proapoptotic BH3-only protein BCL-2 modifying factor prolongs the fertile life span in female mice.Comparative analysis of the metaphase II spindle of human oocytes through polarized light and high-performance confocal microscopy.Permeability of human oocytes to ethylene glycol and their survival and spindle configurations after slow cooling cryopreservation.Ovarian reserve screening: a scientific and ethical analysis.What is the "ovarian reserve"?Primordial follicle activation and follicular development in the juvenile rabbit ovary.KIT/KIT ligand in mammalian oogenesis and folliculogenesis: roles in rabbit and murine ovarian follicle activation and oocyte growth.PUMA regulates germ cell loss and primordial follicle endowment in mice.Examination of the ovotoxicity of 5-fluorouracil in mice.Loss of PUMA protects the ovarian reserve during DNA-damaging chemotherapy and preserves fertility.Dacarbazine depletes the ovarian reserve in mice and depletion is enhanced with age.Oocytes from stem cellsMethylation of all BRCA1 copies predicts response to the PARP inhibitor rucaparib in ovarian carcinomaThe capacity of oocytes for DNA repairMaternal low-protein diet programmes low ovarian reserve in offspringMultidose 5-Fluorouracil is Highly Toxic to Growing Ovarian Follicles in MiceVincristine Chemotherapy Induces Atresia of Growing Ovarian Follicles in Mice
P50
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P50
description
researcher ORCID ID = 0000-0002-5111-8389
@en
wetenschapper
@nl
name
Karla J Hutt
@ast
Karla J Hutt
@en
Karla J Hutt
@nl
type
label
Karla J Hutt
@ast
Karla J Hutt
@en
Karla J Hutt
@nl
prefLabel
Karla J Hutt
@ast
Karla J Hutt
@en
Karla J Hutt
@nl
P31
P496
0000-0002-5111-8389