about
Azapropellanes with anti-influenza a virus activity.Synthesis and pharmacological evaluation of (2-oxaadamant-1-yl)amines.Synthesis and Anti-influenza A Virus Activity of 2,2-Dialkylamantadines and Related Compounds.Slow but Steady Wins the Race: Dissimilarities among New Dual Inhibitors of the Wild-Type and the V27A Mutant M2 Channels of Influenza A Virus.Mechanism of the Pseudoirreversible Binding of Amantadine to the M2 Proton Channel.Antibacterial activity of novel benzopolycyclic amines.3-Azatetracyclo[5.2.1.1(5,8).0(1,5)]undecane derivatives: from wild-type inhibitors of the M2 ion channel of influenza A virus to derivatives with potent activity against the V27A mutant.Easily accessible polycyclic amines that inhibit the wild-type and amantadine-resistant mutants of the M2 channel of influenza A virus.New polycyclic dual inhibitors of the wild type and the V27A mutant M2 channel of the influenza A virus with unexpected binding mode.Synthesis of benzopolycyclic cage amines: NMDA receptor antagonist, trypanocidal and antiviral activities.Role of the viral hemagglutinin in the anti-influenza virus activity of newly synthesized polycyclic amine compounds.Polycyclic N-benzamido imides with potent activity against vaccinia virus.Alternative syntheses of the new D2d symmetric tetramethyl tricyclo- [3.3.0.0(3,7)]octane-1,3,5,7-tetracarboxylate.Generation and reactions of two new functionalized tricyclo[3.3.0.0 3,7]oct-1(5)-ene derivatives.Aniline-based inhibitors of influenza H1N1 virus acting on hemagglutinin-mediated fusion.Towards a Novel Class of Multitarget-Directed Ligands: Dual P2X7-NMDA Receptor Antagonists.Design, synthesis and in vivo study of novel pyrrolidine-based 11β-HSD1 inhibitors for age-related cognitive dysfunction.Escape from adamantane: Scaffold optimization of novel P2X7 antagonists featuring complex polycycles.Novel 11β-HSD1 inhibitors: C-1 versus C-2 substitution and effect of the introduction of an oxygen atom in the adamantane scaffoldSearching for novel applications of the benzohomoadamantane scaffold in medicinal chemistry: Synthesis of novel 11β-HSD1 inhibitorsExploring N-acyl-4-azatetracyclo[5.3.2.02,6.08,10]dodec-11-enes as 11β-HSD1 Inhibitors.Pentafluorosulfanyl-containing Triclocarban Analogs with Potent Antimicrobial ActivityNovel Quinazolinone Inhibitors of ALK2 Flip between Alternate Binding Modes: Structure-Activity Relationship, Structural Characterization, Kinase Profiling, and Cellular Proof of ConceptNovel benzopolycyclic amines with NMDA receptor antagonist activityDimerization of pyramidalized 3,4,8,9-tetramethyltetracyclo [4.4.0.0(3,9).0(4,8)]dec-1(6)-ene to a hydrocarbon featuring four cyclohexane rings in boat conformationsPharmacological and Electrophysiological Characterization of Novel NMDA Receptor AntagonistsPalladium-catalyzed cocyclotrimerization of arynes with a pyramidalized alkeneA Novel NMDA Receptor Antagonist Protects against Cognitive Decline Presented by Senescent MiceSoluble Epoxide Hydrolase Inhibition to Face Neuroinflammation in Parkinson's Disease: A New Therapeutic Strategy
P50
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P50
description
researcher ORCID ID = 0000-0002-9296-6026
@en
name
Santiago Vazquez
@ast
Santiago Vazquez
@en
Santiago Vazquez
@es
Santiago Vazquez
@nl
type
label
Santiago Vazquez
@ast
Santiago Vazquez
@en
Santiago Vazquez
@es
Santiago Vazquez
@nl
prefLabel
Santiago Vazquez
@ast
Santiago Vazquez
@en
Santiago Vazquez
@es
Santiago Vazquez
@nl
P214
P244
P1153
57034307500
P1580
P21
P214
P244
ns2018003082
P31
P496
0000-0002-9296-6026
P735
P7859
lccn-ns2018003082