about
Phenotypic evaluation and in silico ADMET properties of novel arylimidamides in acute mouse models of Trypanosoma cruzi infection.The new pyrazolyltetrazole derivative MSN20 is effective via oral delivery against cutaneous leishmaniasisPterocarpanquinone LQB-118 induces apoptosis in Leishmania (Viannia) braziliensis and controls lesions in infected hamsters.Cyclobenzaprine Raises ROS Levels in Leishmania infantum and Reduces Parasite Burden in Infected Mice.Preclinical Studies Evaluating Subacute Toxicity and Therapeutic Efficacy of LQB-118 in Experimental Visceral Leishmaniasis.Antileishmanial Activity of Ezetimibe: Inhibition of Sterol Biosynthesis, In Vitro Synergy with Azoles, and Efficacy in Experimental Cutaneous LeishmaniasisPterocarpanquinones, aza-pterocarpanquinone and derivatives: synthesis, antineoplasic activity on human malignant cell lines and antileishmanial activity on Leishmania amazonensis.Oral effectiveness of PMIC4, a novel hydroxyethylpiperazine analogue, in Leishmania amazonensisSupercritical Fluid Extraction of Pyrrolidine Alkaloid from Leaves of Piper amalago L.The Trypanocidal Effect of Novel Quinolines: In vitro And In vivo Studies.Leishmaniasis treatment: update of possibilities for drug repurposing.Second-generation pterocarpanquinones: synthesis and antileishmanial activityThe pharmacological inhibition of sterol biosynthesis in Leishmania is counteracted by enhancement of LDL endocytosisLQB-118, an orally active pterocarpanquinone, induces selective oxidative stress and apoptosis in Leishmania amazonensis
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description
researcher ORCID ID = 0000-0002-2833-1771
@en
wetenschapper
@nl
name
Edézio Ferreira Cunha-Junior
@ast
Edézio Ferreira Cunha-Junior
@en
Edézio Ferreira Cunha-Junior
@es
Edézio Ferreira Cunha-Junior
@nl
type
label
Edézio Ferreira Cunha-Junior
@ast
Edézio Ferreira Cunha-Junior
@en
Edézio Ferreira Cunha-Junior
@es
Edézio Ferreira Cunha-Junior
@nl
prefLabel
Edézio Ferreira Cunha-Junior
@ast
Edézio Ferreira Cunha-Junior
@en
Edézio Ferreira Cunha-Junior
@es
Edézio Ferreira Cunha-Junior
@nl
P1153
38662293300
P31
P496
0000-0002-2833-1771