about
Targeting BCL-2 with the BH3 mimetic ABT-199 in estrogen receptor-positive breast cancerEssential role for a novel population of binucleated mammary epithelial cells in lactation.Transcriptome analyses of mouse and human mammary cell subpopulations reveal multiple conserved genes and pathwaysIntegration of microRNA signatures of distinct mammary epithelial cell types with their gene expression and epigenetic portraitsEGF-mediated induction of Mcl-1 at the switch to lactation is essential for alveolar cell survival.RANK ligand as a potential target for breast cancer prevention in BRCA1-mutation carriers.Elementary: breast cancer culprits leave their signatures on the double helix.FOXC1 is enriched in the mammary luminal progenitor population, but is not necessary for mouse mammary ductal morphogenesis.Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers.Identification of quiescent and spatially restricted mammary stem cells that are hormone responsive.Control of mammary stem cell function by steroid hormone signalling.Construction of developmental lineage relationships in the mouse mammary gland by single-cell RNA profiling.Differential methylation analysis of reduced representation bisulfite sequencing experiments using edgeR.Synergistic action of the MCL-1 inhibitor S63845 with current therapies in preclinical models of triple-negative and HER2-amplified breast cancer.Notch signaling regulates mammary stem cell function and luminal cell-fate commitment.Global changes in the mammary epigenome are induced by hormonal cues and coordinated by Ezh2.Canonical PRC2 function is essential for mammary gland development and affects chromatin compaction in mammary organoidsBarcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancerPro-apoptotic Bim suppresses breast tumor cell metastasis and is a target gene of SNAI2Publisher Correction: Barcoding reveals complex clonal behavior in patient-derived xenografts of metastatic triple negative breast cancerFoxp1 Is Indispensable for Ductal Morphogenesis and Controls the Exit of Mammary Stem Cells from QuiescenceIntraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D ImagingIntraclonal Plasticity in Mammary Tumors Revealed through Large-Scale Single-Cell Resolution 3D ImagingTargeting triple-negative breast cancers with the Smac-mimetic birinapantTissue-resident ductal macrophages survey the mammary epithelium and facilitate tissue remodelling
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description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Bhupinder Pal
@ast
Bhupinder Pal
@en
Bhupinder Pal
@es
Bhupinder Pal
@nl
type
label
Bhupinder Pal
@ast
Bhupinder Pal
@en
Bhupinder Pal
@es
Bhupinder Pal
@nl
prefLabel
Bhupinder Pal
@ast
Bhupinder Pal
@en
Bhupinder Pal
@es
Bhupinder Pal
@nl
P106
P1153
15840087200
P31
P496
0000-0002-3684-4331