about
The endoplasmic reticulum is a key component of the plasma cell death pathwayInterleukin 10 is a potent growth and differentiation factor for activated human B lymphocytesCell therapy to induce allograft tolerance: time to switch to plan B?BCR ligation reprograms B cells for migration to the T zone and B-cell follicle sequentiallyMature IgM-expressing plasma cells sense antigen and develop competence for cytokine production upon antigenic challengeInvolvement of BAFF and APRIL in the resistance to apoptosis of B-CLL through an autocrine pathway.Compromising the unfolded protein response induces autophagy-mediated cell death in multiple myeloma cells.Death-receptor contribution to the germinal-center reaction.Mature B cells: apoptosis checkpoints.Interleukin 10 and transforming growth factor beta cooperate to induce anti-CD40-activated naive human B cells to secrete immunoglobulin A.Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosisFLICE-inhibitory protein is a key regulator of germinal center B cell apoptosis.Human interleukin 4.Regulation of germinal center B cell differentiation. Role of the human APO-1/Fas (CD95) molecule.CD1d-restricted peripheral T cell lymphoma in mice and humans.Am"B"valent: anti-CD20 antibodies unravel the dual role of B cells in immunopathogenesis.T cell-independent B cell memory.A Lentiviral Vector Allowing Physiologically Regulated Membrane-anchored and Secreted Antibody Expression Depending on B-cell Maturation Status.Antiproliferative effects of interleukin-4 on freshly isolated non-Hodgkin malignant B-lymphoma cells.Responsiveness of chronic lymphocytic leukemia B cells activated via surface Igs or CD40 to B-cell tropic factors.B Cells Loaded with Synthetic Particulate Antigens: A Versatile Platform To Generate Antigen-Specific Helper T Cells for Cell Therapy.Plasmacytoid dendritic cells are dispensable for noninfectious intestinal IgA responses in vivo.Activation sensitizes human memory B cells to B-cell receptor-induced apoptosis.The vitronectin receptor (alpha v beta 3) is implicated, in cooperation with P-selectin and platelet-activating factor, in the adhesion of monocytes to activated endothelial cellsFas-dependent and Fas-independent mechanisms for selection of the mature human B cell repertoire.Interleukin 13 is a B cell stimulating factor.Interleukin 4 inhibits the proliferation but not the differentiation of activated human B cells in response to interleukin 2.Human recombinant interleukin 4 induces Fc epsilon receptors (CD23) on normal human B lymphocytes.The response of selected human B cell lines to B cell growth and differentiation factors.The origin of the plasma-cell heterogeneity.Toll-like receptor agonists allow generation of long-lasting antipneumococcal humoral immunity in response to a plain polysaccharidic vaccine.Human interferon-gamma acts as a B cell growth factor in the anti-IgM antibody co-stimulatory assay but has no direct B cell differentiation activity.Response of LFA-1-deficient B cells to interleukin 4 (BSF-1) and low molecular weight B cell growth factor (BCGFlow).Triggering of CD40 antigen inhibits fludarabine-induced apoptosis in B chronic lymphocytic leukemia cells.Modulation and functional involvement of CB2 peripheral cannabinoid receptors during B-cell differentiation.Endothelial chimerism and vascular sequestration protect pancreatic islet grafts from antibody-mediated rejection.Mouse and Human Liver Contain Immunoglobulin A-Secreting Cells Originating From Peyer's Patches and Directed Against Intestinal Antigens.CD4+ T Cell Help Is Mandatory for Naive and Memory Donor-Specific Antibody Responses: Impact of Therapeutic Immunosuppression.The thymus-independent immunity conferred by a pneumococcal polysaccharide is mediated by long-lived plasma cells.Mitochondria connects the antigen receptor to effector caspases during B cell receptor-induced apoptosis in normal human B cells.
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P50
description
researcher
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wetenschapper
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հետազոտող
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name
Thierry Defrance
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Thierry Defrance
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Thierry Defrance
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Thierry Defrance
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label
Thierry Defrance
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Thierry Defrance
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Thierry Defrance
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Thierry Defrance
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Thierry Defrance
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Thierry Defrance
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Thierry Defrance
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Thierry Defrance
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P106
P31
P3762
P496
0000-0002-6943-358X