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A six months exercise intervention influences the genome-wide DNA methylation pattern in human adipose tissueEpigenetic regulation of PPARGC1A in human type 2 diabetic islets and effect on insulin secretionExpression of phosphofructokinase in skeletal muscle is influenced by genetic variation and associated with insulin sensitivityGenetic variation in ATP5O is associated with skeletal muscle ATP50 mRNA expression and glucose uptake in young twinsGenetic and epigenetic factors are associated with expression of respiratory chain component NDUFB6 in human skeletal muscleInvestigation of type 2 diabetes risk alleles support CDKN2A/B, CDKAL1, and TCF7L2 as susceptibility genes in a Han Chinese cohort.Effects of palmitate on genome-wide mRNA expression and DNA methylation patterns in human pancreatic islets.Genome-wide associations between genetic and epigenetic variation influence mRNA expression and insulin secretion in human pancreatic islets.Sex differences in the genome-wide DNA methylation pattern and impact on gene expression, microRNA levels and insulin secretion in human pancreatic islets.Two common genetic variants near nuclear-encoded OXPHOS genes are associated with insulin secretion in vivo.Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.Genome-wide analysis of DNA methylation in subjects with type 1 diabetes identifies epigenetic modifications associated with proliferative diabetic retinopathyA Genome-Wide mQTL Analysis in Human Adipose Tissue Identifies Genetic Variants Associated with DNA Methylation, Gene Expression and Metabolic Traits.Impact of an exercise intervention on DNA methylation in skeletal muscle from first-degree relatives of patients with type 2 diabetes.Less pronounced response to exercise in healthy relatives to type 2 diabetic subjects compared with controlsIdentification of CpG-SNPs associated with type 2 diabetes and differential DNA methylation in human pancreatic isletsTelomere length in blood and skeletal muscle in relation to measures of glycaemia and insulinaemia.Epigenetic adaptation to regular exercise in humans.DNA methylation as a diagnostic and therapeutic target in the battle against Type 2 diabetes.Leveraging cross-species transcription factor binding site patterns: from diabetes risk loci to disease mechanisms.Epigenetic alterations in blood mirror age-associated DNA methylation and gene expression changes in human liver.A common variant in TFB1M is associated with reduced insulin secretion and increased future risk of type 2 diabetes.A common variant in MTNR1B, encoding melatonin receptor 1B, is associated with type 2 diabetes and fasting plasma glucose in Han Chinese individuals.Altered DNA methylation and differential expression of genes influencing metabolism and inflammation in adipose tissue from subjects with type 2 diabetes.Deoxyribonucleic acid methylation and gene expression of PPARGC1A in human muscle is influenced by high-fat overfeeding in a birth-weight-dependent manner.Effect of exercise on DNA methylation and metabolism in human adipose tissue and skeletal muscle.Epigenetic markers to further understand insulin resistance.PPARGC1A DNA methylation in subcutaneous adipose tissue in low birth weight subjects--impact of 5 days of high-fat overfeeding.Whole-Genome Bisulfite Sequencing of Human Pancreatic Islets Reveals Novel Differentially Methylated Regions in Type 2 Diabetes Pathogenesis.Human liver epigenetic alterations in non-alcoholic steatohepatitis are related to insulin action.Unique splicing pattern of the TCF7L2 gene in human pancreatic islets.Adipose tissue transcriptomics and epigenomics in low birthweight men and controls: role of high-fat overfeeding.First-Degree Relatives of Type 2 Diabetic Patients Have Reduced Expression of Genes Involved in Fatty Acid Metabolism in Skeletal MuscleAge influences DNA methylation and gene expression of COX7A1 in human skeletal muscleExtensive changes in the transcriptional profile of human adipose tissue including genes involved in oxidative phosphorylation after a 6-month exercise intervention
P50
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P50
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P106
P1153
22981252600
P31
P496
0000-0001-7622-800X