about
NLRP3 inflammasome plays a key role in the regulation of intestinal homeostasis.The airway epithelium nucleotide-binding domain and leucine-rich repeat protein 3 inflammasome is activated by urban particulate matter.Hypoxia-inducible factor signaling provides protection in Clostridium difficile-induced intestinal injury.Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis.Intrarectal instillation of Clostridium difficile toxin A triggers colonic inflammation and tissue damage: development of a novel and efficient mouse model of Clostridium difficile toxin exposure.Targeting hypoxia-inducible factor-1 (HIF-1) signaling in therapeutics: implications for the treatment of inflammatory bowel disease.Effects of nitric oxide and reactive oxygen species on HIF-1α stabilization following clostridium difficile toxin exposure of the Caco-2 epithelial cell line.Clostridium difficile toxin-induced inflammation and intestinal injury are mediated by the inflammasome.The P2Y6 receptor mediates Clostridium difficile toxin-induced CXCL8/IL-8 production and intestinal epithelial barrier dysfunction.Vitamin D₃ metabolites enhance the NLRP3-dependent secretion of IL-1β from human THP-1 monocytic cells.The Nlrp3 inflammasome promotes myocardial dysfunction in structural cardiomyopathy through interleukin-1β.Mitogen-activated protein kinase pathways contribute to hypercontractility and increased Ca2+ sensitization in murine experimental colitis.
P50
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P50
name
Paul L Beck
@ast
Paul L Beck
@en
Paul L Beck
@nl
type
label
Paul L Beck
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Paul L Beck
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Paul L Beck
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prefLabel
Paul L Beck
@ast
Paul L Beck
@en
Paul L Beck
@nl