about
Binding of a Cyano- and Fluoro-containing Drug Bicalutamide to Cytochrome P450 46A1: UNUSUAL FEATURES AND SPECTRAL RESPONSEProlonged exposure to (R)-bicalutamide generates a LNCaP subclone with alteration of mitochondrial genome.Interaction mechanism exploration of R-bicalutamide/S-1 with WT/W741L AR using molecular dynamics simulations.Molecular mechanism of R-bicalutamide switching from androgen receptor antagonist to agonist induced by amino acid mutations using molecular dynamics simulations and free energy calculation.Pharmacokinetics of two novel bicalutamide formulations in healthy male volunteers.
P921
description
chemesch Verbindung
@lb
chemical compound
@en
chemical compound
@en-ca
chemical compound
@en-gb
chemická sloučenina
@cs
chemická zlúčenina
@sk
chemiese verbinding
@af
chemische Verbindung
@de
chemische Verbindung
@de-ch
chemische verbinding
@nl
name
(R)-bicalutamide
@en
type
label
(R)-bicalutamide
@en
prefLabel
(R)-bicalutamide
@en
P6689
P662
P683
P2017
C[C@](CS(=O)(=O)C1=CC=C(C=C1)F)(C(=O)NC2=CC(=C(C=C2)C#N)C(F)(F)F)O
P234
1S/C18H14F4N2O4S/c1-17(26,10-2 ...... ,10H2,1H3,(H,24,25)/t17-/m0/s1
P235
LKJPYSCBVHEWIU-KRWDZBQOSA-N
P274
C₁₈H₁₄F₄N₂O₄S