about
A Genome-wide multidimensional RNAi screen reveals pathways controlling MHC class II antigen presentationActivation of endosomal dynein motors by stepwise assembly of Rab7-RILP-p150Glued, ORP1L, and the receptor betalll spectrinAn ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport.Drug-induced histone eviction from open chromatin contributes to the chemotherapeutic effects of doxorubicin.Cholesterol-binding molecules MLN64 and ORP1L mark distinct late endosomes with transporters ABCA3 and NPC1The Rab7 effector protein RILP controls lysosomal transport by inducing the recruitment of dynein-dynactin motors.A major role for TPPII in trimming proteasomal degradation products for MHC class I antigen presentation.A splice variant of RILP induces lysosomal clustering independent of dynein recruitment.The first step of peptide selection in antigen presentation by MHC class I molecules.Definition of Proteasomal Peptide Splicing Rules for High-Efficiency Spliced Peptide Presentation by MHC Class I MoleculesCutting edge: HLA-B27 acquires many N-terminal dibasic peptides: coupling cytosolic peptide stability to antigen presentation.Dynein-mediated vesicle transport controls intracellular Salmonella replication.Interaction between Tiam1 and the Arp2/3 complex links activation of Rac to actin polymerization.Genome-Wide Identification and Characterization of Novel Factors Conferring Resistance to Topoisomerase II Poisons in Cancer.Expression of Rho GTPases using retroviral vectors.Homeostasis of soluble proteins and the proteasome post nuclear envelope reformation in mitosis
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P50
description
researcher
@en
wetenschapper
@nl
հետազոտող
@hy
name
Lennert Janssen
@ast
Lennert Janssen
@en
Lennert Janssen
@es
Lennert Janssen
@nl
type
label
Lennert Janssen
@ast
Lennert Janssen
@en
Lennert Janssen
@es
Lennert Janssen
@nl
prefLabel
Lennert Janssen
@ast
Lennert Janssen
@en
Lennert Janssen
@es
Lennert Janssen
@nl
P106
P31
P496
0000-0001-9705-0204