about
Tambjamine alkaloids and related synthetic analogs: efficient transmembrane anion transporters.Molecular interactions of prodiginines with the BH3 domain of anti-apoptotic Bcl-2 family membersSynthetic tambjamine analogues induce mitochondrial swelling and lysosomal dysfunction leading to autophagy blockade and necrotic cell death in lung cancer.Facilitated Anion Transport Induces Hyperpolarization of the Cell Membrane That Triggers Differentiation and Cell Death in Cancer Stem Cells.Transmembrane anion transport and cytotoxicity of synthetic tambjamine analogs.Identification of dual mTORC1 and mTORC2 inhibitors in melanoma cells: prodigiosin vs. obatoclax.Using small molecules to facilitate exchange of bicarbonate and chloride anions across liposomal membranes.A calixarene dendron with surface congestion at the first generation.Simple 1-dicyanomethylene-2-chloro-3-aminoindene push-pull chromophores: applications in cation and anion sensing.Insertion of thiocyanogen into a P-C bond and subsequent formation of polysulfide derivatives.P-C versus C-H bond cleavage in coordinated bis(dimethylphosphino)methane: controlled access to either phosphinite or functionalized diphosphine complexes.Inhibition of Human Enhancer of Zeste Homolog 2 with Tambjamine Analogs.Novel pyrrolobenzodiazepine and pyrroloquinazoline scaffolds synthesized by a simple and highly selective Ugi/cyclization sequence.Small molecule anionophores promote transmembrane anion permeation matching CFTR activity.Novel Indole-based Tambjamine-Analogues Induce Apoptotic Lung Cancer Cell Death through p38 Mitogen-Activated Protein Kinase Activation.Colonization of Electrospun Polycaprolactone Fibers by Relevant Pathogenic Bacterial Strains.Conformational control of transmembrane Cl(-) transport.Base induced P-C bond cleavage in a coordinated bis(dimethylphosphino)methane ligand.QSAR analysis of substituent effects on tambjamine anion transporters.Thiocyanogen Insertion into P−C Bonds of Diphosphinomethanide Complexes, Leading to Rare Functionalized Diphosphine and Tetraphosphine LigandsConformational Analysis of a Model Synthetic ProdiginineAnion-Transport Mechanism of a Triazole-Bearing Derivative of Prodigiosine: A Candidate for Cystic Fibrosis TherapySubstituted pyridazines as ligands in homoleptic (fac and mer) and heteroleptic Ru(II) complexes1,8-Diamidocarbazoles: an easily tuneable family of fluorescent anion sensors and transportersClick-tambjamines as efficient and tunable bioactive anion transportersTargeting Autophagy for Cancer Treatment and Tumor ChemosensitizationpH-Dependent Chloride Transport by Pseudopeptidic Cages for the Selective Killing of Cancer Cells in Acidic MicroenvironmentsSmall molecule-facilitated anion transporters in cells for a novel therapeutic approach to cystic fibrosisSmall molecule anion transporters display in vitro antimicrobial activity against clinically relevant bacterial strainsThe Natural-Based Antitumor Compound T21 Decreases Survivin Levels through Potent STAT3 Inhibition in Lung Cancer ModelsTherapeutic strategies involving survivin inhibition in cancer
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Roberto Quesada
@ast
Roberto Quesada
@en
Roberto Quesada
@es
Roberto Quesada
@nl
type
label
Roberto Quesada
@ast
Roberto Quesada
@en
Roberto Quesada
@es
Roberto Quesada
@nl
prefLabel
Roberto Quesada
@ast
Roberto Quesada
@en
Roberto Quesada
@es
Roberto Quesada
@nl
P106
P1153
10538779000
P31
P496
0000-0003-2764-7157