about
Monitoring of indirect allorecognition: wishful thinking or solid data?PRAME as a Potential Target for Immunotherapy in Metastatic Uveal Melanoma.Generating HPV specific T helper cells for the treatment of HPV induced malignancies using TCR gene transfer.Generation of CD20-specific TCRs for TCR gene therapy of CD20low B-cell malignancies insusceptible to CD20-targeting antibodies.Conditional MHC class I ligands and peptide exchange technology for the human MHC gene products HLA-A1, -A3, -A11, and -B7T-cell receptor gene transfer for treatment of leukemia.TCR-based therapy for multiple myeloma and other B-cell malignancies targeting intracellular transcription factor BOB1.Discovery of T cell epitopes implementing HLA-peptidomics into a reverse immunology approach.Pulmonary immune responses against Aspergillus fumigatus are characterized by high frequencies of IL-17 producing T-cells.CLEC12A-Mediated Antigen Uptake and Cross-Presentation by Human Dendritic Cell Subsets Efficiently Boost Tumor-Reactive T Cell Responses.A CD22-reactive TCR from the T-cell allorepertoire for the treatment of acute lymphoblastic leukemia by TCR gene transfer.Selective graft-versus-leukemia depends on magnitude and diversity of the alloreactive T cell response.Characterization of the T-cell-mediated immune response against the Aspergillus fumigatus proteins Crf1 and catalase 1 in healthy individuals.Strong selection of virus-specific cytotoxic CD4+ T-cell clones during primary human cytomegalovirus infection.Specific T-cell Responses Against Minor Histocompatibility Antigens Cannot Generally Be Explained by Absence of Their Allelic Counterparts on the Cell Surface.Identification of Biological Relevant Minor Histocompatibility Antigens within the B-lymphocyte-Derived HLA-Ligandome Using a Reverse Immunology Approach.Rapid assessment of the antigenic integrity of tetrameric HLA complexes by human monoclonal HLA antibodies.Preclinical Strategies to Identify Off-Target Toxicity of High-Affinity TCRs.A Jurkat 76 based triple parameter reporter system to evaluate TCR functions and adoptive T cell strategies.Adoptive immunotherapy using PRAME-specific T cells in medulloblastomaPretransplantation CMV-specific T cells protect recipients of T-cell-depleted grafts against CMV-related complicationsIdentification of non-mutated neoantigens presented by TAP-deficient tumors.Allogeneic HLA-A*02-restricted WT1-specific T cells from mismatched donors are highly reactive but show off-target promiscuitymicroRNA 125a Regulates MHC-I Expression on Esophageal Adenocarcinoma Cells, Associated With Suppression of Antitumor Immune Response and Poor Outcomes of PatientsFramework engineering to produce dominant T cell receptors with enhanced antigen-specific functionImmunopeptidome Analysis of HLA-DPB1 Allelic Variants Reveals New Functional Hierarchies
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description
researcher
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wetenschapper
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հետազոտող
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name
Mirjam H.M. Heemskerk
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Mirjam H.M. Heemskerk
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Mirjam H.M. Heemskerk
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Mirjam H.M. Heemskerk
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type
label
Mirjam H.M. Heemskerk
@ast
Mirjam H.M. Heemskerk
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Mirjam H.M. Heemskerk
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Mirjam H.M. Heemskerk
@nl
prefLabel
Mirjam H.M. Heemskerk
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Mirjam H.M. Heemskerk
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Mirjam H.M. Heemskerk
@es
Mirjam H.M. Heemskerk
@nl
P106
P31
P496
0000-0001-6320-9133