about
Recent advances in the semi-pinacol rearrangement of alpha-hydroxy epoxides and related compounds.A truce on the Smiles rearrangement: revisiting an old reaction--the Truce-Smiles rearrangement.2-Arylindoles: a privileged molecular scaffold with potent, broad-ranging pharmacological activity.Small-molecule clinical trial candidates for the treatment of glioma.Heterocyclic scaffolds as promising anticancer agents against tumours of the central nervous system: Exploring the scope of indole and carbazole derivatives.Approaches toward improving the prognosis of pediatric patients with glioma: pursuing mutant drug targets with emerging small molecules.Anionic Host Defence Peptides from the Plant Kingdom: Their Anticancer Activity and Mechanisms of Action.Cn-AMP2 from green coconut water is an anionic anticancer peptide.Development of a novel, multifunctional, membrane-interactive pyridinium salt with potent anticancer activity.Preliminary biological evaluation and mechanism of action studies of selected 2-arylindoles against glioblastoma.Functional foldamers that target bacterial membranes: The effect of charge, amphiphilicity and conformation.Functionalising the azobenzene motif delivers a light-responsive membrane-interactive compound with the potential for photodynamic therapy applications.Helix persistence and breakdown in oligoureas of metaphenylenediamine: apparent diastereotopicity as a spectroscopic marker of helix length in solution.Foldamers as Anticancer Therapeutics: Targeting Protein-Protein Interactions and the Cell Membrane.Synthetic oligoureas of metaphenylenediamine mimic host defence peptides in their antimicrobial behaviour.Enzymatic Oxidation ChemistryA template-based mnemonic for monoamine oxidase (MAO-N) catalyzed reactions and its application to the chemo-enzymatic deracemisation of the alkaloid (±)-crispine AAchieving conformational control over C–C, C–N and C–O bonds in biaryls, N,N′-diarylureas and diaryl ethers: advantages of a relay axisApplication of the semi-pinacol rearrangement towards the generation of alkenyl-substituted quaternary carbon centresInduction of apoptosis in estrogen receptor-negative breast cancer cells by natural and synthetic cyclopentenones: role of the IkappaB kinase/nuclear factor-kappaB pathwayAromatic amides and ureas as novel molecular probes for diagnosing diseaseTowards identifying potent new hits for glioblastomaIdentification of C-β-d-Glucopyranosyl Azole-Type Inhibitors of Glycogen Phosphorylase That Reduce Glycogenolysis in Hepatocytes: In Silico Design, Synthesis, in Vitro Kinetics, and ex Vivo Studies
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description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Timothy J. Snape
@ast
Timothy J. Snape
@en
Timothy J. Snape
@es
Timothy J. Snape
@nl
type
label
Timothy J. Snape
@ast
Timothy J. Snape
@en
Timothy J. Snape
@es
Timothy J. Snape
@nl
prefLabel
Timothy J. Snape
@ast
Timothy J. Snape
@en
Timothy J. Snape
@es
Timothy J. Snape
@nl
P106
P1153
35234896700
P31
P496
0000-0003-2766-4491