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Three-Dimensional Reconstruction of Tarantula Myosin Filaments Suggests How Phosphorylation May Regulate Myosin ActivityOutcome of the first electron microscopy validation task force meetingConventions and workflows for using SitusSitus: A package for docking crystal structures into low-resolution maps from electron microscopyActin depolymerizing factor stabilizes an existing state of F-actin and can change the tilt of F-actin subunitsNumerical geometry of map and model assessment.Comparison of an Atomic Model and Its Cryo-EM Image at the Central Axis of a HelixComparing an Atomic Model or Structure to a Corresponding Cryo-electron Microscopy Image at the Central Axis of a Helix.Biomolecular pleiomorphism probed by spatial interpolation of coarse models.Automated tracing of filaments in 3D electron tomography reconstructions using Sculptor and Situs.Developing a denoising filter for electron microscopy and tomography data in the cloud.Structure and dynamics of calmodulin in solution.2D fast rotational matching for image processing of biophysical data.Bend-twist-stretch model for coarse elastic network simulation of biomolecular motion.Computing Spatiotemporal Heat Maps of Lipid Electropore Formation: A Statistical ApproachA Balanced Approach to Adaptive Probability Density EstimationConformational flexibility of bacterial RNA polymerase.Nucleotide-dependent movements of the kinesin motor domain predicted by simulated annealing.Domain motions of EF-G bound to the 70S ribosome: insights from a hand-shaking between multi-resolution structuresLike-charge attraction between polyelectrolytes induced by counterion charge density wavesEvolutionary bidirectional expansion for the tracing of alpha helices in cryo-electron microscopy reconstructions.Multi-scale Visualization of Molecular Architecture Using Real-Time Ambient Occlusion in SculptorUsing Sculptor and Situs for simultaneous assembly of atomic components into low-resolution shapesControl of protein functional dynamics by peptide linkers.Conserved Intramolecular Interactions Maintain Myosin Interacting-Heads Motifs Explaining Tarantula Muscle Super-Relaxed State Structural Basis.Spatial Heat Maps from Fast Information Matching of Fast and Slow Degrees of Freedom: Application to Molecular Dynamics Simulations.Matching structural densities from different biophysical origins with gain and bias.Limulus polyphemus hemocyanin: 10 A cryo-EM structure, sequence analysis, molecular modelling and rigid-body fitting reveal the interfaces between the eight hexamers.Exploring global distortions of biological macromolecules and assemblies from low-resolution structural information and elastic network theory.Cross-linking constraints on F-actin structure.Regulation of yeast actin behavior by interaction of charged residues across the interdomain cleft.Self-organizing neural networks bridge the biomolecular resolution gap.Cofilin and gelsolin segment-1: molecular dynamics simulation and biochemical analysis predict a similar actin binding mode.Interactive fitting augmented by force-feedback and virtual reality.Conformations of variably linked chimeric proteins evaluated by synchrotron X-ray small-angle scattering.Direct observation of counterion organization in F-actin polyelectrolyte bundles.Multi-resolution anchor-point registration of biomolecular assemblies and their components.Tracing Actin Filament Bundles in Three-Dimensional Electron Tomography Density Maps of Hair Cell Stereocilia.Fast rotational matching of rigid bodies by fast Fourier transform acceleration of five degrees of freedomMega-Dalton Biomolecular Motion Captured from Electron Microscopy Reconstructions
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Forscher
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