about
Metazoan Hsp70-based protein disaggregases: emergence and mechanismsCdc37 has distinct roles in protein kinase quality control that protect nascent chains from degradation and promote posttranslational maturationMetazoan Hsp70 machines use Hsp110 to power protein disaggregationCrucial HSP70 co-chaperone complex unlocks metazoan protein disaggregation.Monitoring protein misfolding by site-specific labeling of proteins in vivoA targeted proteomic analysis of the ubiquitin-like modifier nedd8 and associated proteins.Ydj1 protects nascent protein kinases from degradation and controls the rate of their maturation.Evolution of an intricate J-protein network driving protein disaggregation in eukaryotes.Substrate binding by the yeast Hsp110 nucleotide exchange factor and molecular chaperone Sse1 is not obligate for its biological activities.In vivo properties of the disaggregase function of J-proteins and Hsc70 in Caenorhabditis elegans stress and aging.Hsp70 displaces small heat shock proteins from aggregates to initiate protein refolding.Protein Disaggregation in Multicellular OrganismsFunctional diversity between HSP70 paralogs due to variable interactions with specific co-chaperonesFunction, evolution, and structure of J-domain proteins
P50
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P50
description
onderzoeker
@nl
researcher
@en
հետազոտող
@hy
name
Nadinath B Nillegoda
@ast
Nadinath B Nillegoda
@de
Nadinath B Nillegoda
@en
Nadinath B Nillegoda
@es
Nadinath B Nillegoda
@fr
Nadinath B Nillegoda
@it
Nadinath B Nillegoda
@nl
type
label
Nadinath B Nillegoda
@ast
Nadinath B Nillegoda
@de
Nadinath B Nillegoda
@en
Nadinath B Nillegoda
@es
Nadinath B Nillegoda
@fr
Nadinath B Nillegoda
@it
Nadinath B Nillegoda
@nl
prefLabel
Nadinath B Nillegoda
@ast
Nadinath B Nillegoda
@de
Nadinath B Nillegoda
@en
Nadinath B Nillegoda
@es
Nadinath B Nillegoda
@fr
Nadinath B Nillegoda
@it
Nadinath B Nillegoda
@nl
P106
P1153
15835234900
P31
P496
0000-0002-9980-3991