about
Critical role of regulator G-protein signaling 10 (RGS10) in modulating macrophage M1/M2 activation.Age-related changes in regulator of G-protein signaling (RGS)-10 expression in peripheral and central immune cells may influence the risk for age-related degeneration.Regulator of G-protein signaling-10 negatively regulates NF-κB in microglia and neuroprotects dopaminergic neurons in hemiparkinsonian rats.RGS10 exerts a neuroprotective role through the PKA/c-AMP response-element (CREB) pathway in dopaminergic neuron-like cells.Progranulin does not bind tumor necrosis factor (TNF) receptors and is not a direct regulator of TNF-dependent signaling or bioactivity in immune or neuronal cells.Candidate inflammatory biomarkers display unique relationships with alpha-synuclein and correlate with measures of disease severity in subjects with Parkinson's disease.Synergistic cell death by EGCG and ibuprofen in DU-145 prostate cancer cell line.RGS10 deficiency ameliorates the severity of disease in experimental autoimmune encephalomyelitis.Peripheral administration of the selective inhibitor of soluble tumor necrosis factor (TNF) XPro®1595 attenuates nigral cell loss and glial activation in 6-OHDA hemiparkinsonian rats.Role of protein phosphatases in estrogen-mediated neuroprotection.
P50
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P50
name
Jaegwon Chung
@ast
Jaegwon Chung
@en
Jaegwon Chung
@nl
type
label
Jaegwon Chung
@ast
Jaegwon Chung
@en
Jaegwon Chung
@nl
prefLabel
Jaegwon Chung
@ast
Jaegwon Chung
@en
Jaegwon Chung
@nl