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Transfer of host-derived α synuclein to grafted dopaminergic neurons in ratIntrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degenerationLoss of VGLUT3 Produces Circadian-Dependent Hyperdopaminergia and Ameliorates Motor Dysfunction and l-Dopa-Mediated Dyskinesias in a Model of Parkinson's DiseaseEffect of levodopa priming on dopamine neuron transplant efficacy and induction of abnormal involuntary movements in parkinsonian ratsImpact of dendritic spine preservation in medium spiny neurons on dopamine graft efficacy and the expression of dyskinesias in parkinsonian ratsEtiology of Parkinson's disease: Genetics and environment revisitedRecombinant adenoassociated virus 2/5-mediated gene transfer is reduced in the aged rat midbrain.Chronic amitriptyline treatment attenuates nigrostriatal degeneration and significantly alters trophic support in a rat model of parkinsonismCellular models to study dopaminergic injury responses.The role of alpha-synuclein in Parkinson's disease: insights from animal models.Interrogating the aged striatum: robust survival of grafted dopamine neurons in aging rats produces inferior behavioral recovery and evidence of impaired integrationThe longitudinal transcriptomic response of the substantia nigra to intrastriatal 6-hydroxydopamine reveals significant upregulation of regeneration-associated genes.Sonic Hedgehog Controls the Phenotypic Fate and Therapeutic Efficacy of Grafted Neural Precursor Cells in a Model of Nigrostriatal Neurodegeneration.Striatal pleiotrophin overexpression provides functional and morphological neuroprotection in the 6-hydroxydopamine model.Anatomy of Graft-induced Dyskinesias: Circuit Remodeling in the Parkinsonian StriatumNeural repair strategies for Parkinson's disease: insights from primate models.Advances in thin tissue Golgi-Cox impregnation: fast, reliable methods for multi-assay analyses in rodent and non-human primate brainAberrant restoration of spines and their synapses in L-DOPA-induced dyskinesia: involvement of corticostriatal but not thalamostriatal synapsesImpact of age and vector construct on striatal and nigral transgene expression.Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease.Repairing the Aged Parkinsonian Striatum: Lessons from the Lab and Clinic.Subthalamic nucleus stimulation increases brain derived neurotrophic factor in the nigrostriatal system and primary motor cortex.Is Alpha-Synuclein Loss-of-Function a Contributor to Parkinsonian Pathology? Evidence from Non-human Primates.High-Frequency Stimulation of the Rat Entopeduncular Nucleus Does Not Provide Functional or Morphological Neuroprotection from 6-Hydroxydopamine.Partial dopamine loss enhances activated caspase-3 activity: differential outcomes in striatal projection systems.Primate models of Parkinson's disease.Embryonic mesencephalic grafts increase levodopa-induced forelimb hyperkinesia in parkinsonian rats.Focal not widespread grafts induce novel dyskinetic behavior in parkinsonian rats.Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys.Repairing the Nervous System: A Special Issue Based on the 12th Annual American Society for Neural Therapy and Repair (ASNTR) Meeting.Regulation of dopamine neurotransmission from serotonergic neurons by ectopic expression of the dopamine D2 autoreceptor blocks levodopa-induced dyskinesiaGenetic silencing of striatal CaV1.3 prevents and ameliorates levodopa dyskinesia.
P50
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P50
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Kathy Steece-Collier
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Kathy Steece-Collier
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Kathy Steece-Collier
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Kathy Steece-Collier
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Kathy Steece-Collier
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Kathy Steece-Collier
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K Steece-Collier
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K. Steece-Collier
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Steece-Collier K.
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Steece-Collier
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Kathy Steece-Collier
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Kathy Steece-Collier
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Kathy Steece-Collier
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