about
Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.Persistent amyloidosis following suppression of Abeta production in a transgenic model of Alzheimer diseaseEvi3, a common retroviral integration site in murine B-cell lymphoma, encodes an EBFAZ-related Krüppel-like zinc finger proteinMitf and Tfe3, two members of the Mitf-Tfe family of bHLH-Zip transcription factors, have important but functionally redundant roles in osteoclast development.Pancreatic cancer genomes reveal aberrations in axon guidance pathway genesHermansky-Pudlak syndrome type 7 (HPS-7) results from mutant dysbindin, a member of the biogenesis of lysosome-related organelles complex 1 (BLOC-1)A transposon-based genetic screen in mice identifies genes altered in colorectal cancerZfp423 is required for normal cerebellar development.Murine NFX.1: isolation and characterization of its messenger RNA, mapping of its chromosomal location and assessment of its developmental expressionSimple and highly efficient BAC recombineering using galK selectionVisualization and identification of IL-7 producing cells in reporter miceMutant presenilins specifically elevate the levels of the 42 residue beta-amyloid peptide in vivo: evidence for augmentation of a 42-specific gamma secretaseSynaptic defects in ataxia mice result from a mutation in Usp14, encoding a ubiquitin-specific proteaseEvolution of the regulators of G-protein signaling multigene family in mouse and humanIdentification of an organelle receptor for myosin-VaJxc1/Sobp, encoding a nuclear zinc finger protein, is critical for cochlear growth, cell fate, and patterning of the organ of cortiBcl11a is essential for normal lymphoid developmentdsu functions in a MYO5A-independent pathway to suppress the coat color of dilute miceTranscription factor Bcl11b controls selection of invariant natural killer T-cells by regulating glycolipid presentation in double-positive thymocytesIsolation and characterization of the mouse ubiquitin-specific protease Usp15Ru2 and Ru encode mouse orthologs of the genes mutated in human Hermansky-Pudlak syndrome types 5 and 6The dual specificity JKAP specifically activates the c-Jun N-terminal kinase pathwayBCL11B is required for positive selection and survival of double-positive thymocytesMolecular cloning of mouse collectin liver 1Identification of Vangl2 and Scrb1 as planar polarity genes in mammalsIdentification and characterization of a new pair of immunoglobulin-like receptors LMIR1 and 2 derived from murine bone marrow-derived mast cellsThe E3 ligase Itch negatively regulates inflammatory signaling pathways by controlling the function of the ubiquitin-editing enzyme A20Hematopoietic, angiogenic and eye defects in Meis1 mutant animals.BHLHB4 is a bHLH transcriptional regulator in pancreas and brain that marks the dimesencephalic boundaryA DNA transposon-based approach to validate oncogenic mutations in the mouseTransposon mutagenesis identifies genes and cellular processes driving epithelial-mesenchymal transition in hepatocellular carcinoma.A dual function of Bcl11b/Ctip2 in hippocampal neurogenesis.Human alpha-synuclein-harboring familial Parkinson's disease-linked Ala-53 --> Thr mutation causes neurodegenerative disease with alpha-synuclein aggregation in transgenic mice.Melanoregulin regulates a shedding mechanism that drives melanosome transfer from melanocytes to keratinocytes.Murine leukemias with retroviral insertions at Lmo2 are predictive of the leukemias induced in SCID-X1 patients following retroviral gene therapy.Self-inactivating retroviral vector-mediated gene transfer induces oncogene activation and immortalization of primary murine bone marrow cells.Synphilin-1 attenuates neuronal degeneration in the A53T alpha-synuclein transgenic mouse modelResponse and resistance to MEK inhibition in leukaemias initiated by hyperactive RasTransposon mutagenesis identifies genes driving hepatocellular carcinoma in a chronic hepatitis B mouse modelAntigen-specific clonal expansion and cytolytic effector function of CD8+ T lymphocytes depend on the transcription factor Bcl11b.
P50
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P50
name
Neal G. Copeland
@ast
Neal G. Copeland
@en
Neal G. Copeland
@nl
type
label
Neal G. Copeland
@ast
Neal G. Copeland
@en
Neal G. Copeland
@nl
prefLabel
Neal G. Copeland
@ast
Neal G. Copeland
@en
Neal G. Copeland
@nl