about
Carbohydrate-Binding Non-Peptidic Pradimicins for the Treatment of Acute Sleeping Sickness in Murine ModelsCrystal structure and DNA repair activities of the AP endonuclease from Leishmania majorCell cycle regulation and novel structural features of thymidine kinase, an essential enzyme in Trypanosoma bruceiNew azasterols against Trypanosoma brucei: role of 24-sterol methyltransferase in inhibitor action.Exposure of Trypanosoma brucei to an N-acetylglucosamine-binding lectin induces VSG switching and glycosylation defects resulting in reduced infectivity.Identification of a residue critical for the excision of 3'-blocking ends in apurinic/apyrimidinic endonucleases of the Xth family.In vitro antiplasmodial and cytotoxic activities of asymmetrical pyridinium derivatives.Increased uracil insertion in DNA is cytotoxic and increases the frequency of mutation, double strand break formation and VSG switching in Trypanosoma brucei.Trypanosomes lacking uracil-DNA glycosylase are hypersensitive to antifolates and present a mutator phenotype.Intracellular location of the early steps of the isoprenoid biosynthetic pathway in the trypanosomatids Leishmania major and Trypanosoma brucei.Depletion of dimeric all-alpha dUTPase induces DNA strand breaks and impairs cell cycle progression in Trypanosoma brucei.Pyrimidine requirements in deoxyuridine triphosphate nucleotidohydrolase deficient Trypanosoma brucei mutants.Surface Glycans: A Therapeutic Opportunity for Kinetoplastid Diseases.Surface Glycans: A Therapeutic Opportunity for Kinetoplastid Diseases: (Trends in Parasitology 2017).Endogenous sterol biosynthesis is important for mitochondrial function and cell morphology in procyclic forms of Trypanosoma brucei.
P50
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P50
description
Forscher
@de
chercheur
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investigador
@es
researcher
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ricercatore
@it
研究者
@zh
name
Victor M Castillo-Acosta
@ast
Victor M Castillo-Acosta
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Victor M Castillo-Acosta
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Victor M Castillo-Acosta
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type
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Victor M Castillo-Acosta
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Victor M Castillo-Acosta
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Victor M Castillo-Acosta
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Victor M Castillo-Acosta
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prefLabel
Victor M Castillo-Acosta
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Victor M Castillo-Acosta
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Victor M Castillo-Acosta
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Victor M Castillo-Acosta
@nl
P31
P496
0000-0003-0938-2343