about
Gain- and loss-of-function Lyn mutant mice define a critical inhibitory role for Lyn in the myeloid lineageDifferential binding of an SRF/NK-2/MEF2 transcription factor complex in normal versus neoplastic smooth muscle tissuesMyogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5lgl Regulates the Hippo Pathway Independently of Fat/Dachs, Kibra/Expanded/Merlin and dRASSF/dSTRIPAK.Regulation of Notch signaling and endocytosis by the Lgl neoplastic tumor suppressor.Defining the essential function of FBP/KSRP proteins: Drosophila Psi interacts with the mediator complex to modulate MYC transcription and tissue growthLgl/aPKC and Crb regulate the Salvador/Warts/Hippo pathwayS6 Kinase is essential for MYC-dependent rDNA transcription in Drosophila.Defective Hfp-dependent transcriptional repression of dMYC is fundamental to tissue overgrowth in Drosophila XPB models.A Kinome RNAi Screen in Drosophila Identifies Novel Genes Interacting with Lgl, aPKC, and Crb Cell Polarity Genes in Epithelial Tissues.Lgl regulates Notch signaling via endocytosis, independently of the apical aPKC-Par6-Baz polarity complex.Geminin and Brahma act antagonistically to regulate EGFR-Ras-MAPK signaling in Drosophila.miR-9a mediates the role of Lethal giant larvae as an epithelial growth inhibitor in Drosophila.Lgl, the SWH pathway and tumorigenesis: It's a matter of context & competition!Using Mouse and Models to Investigate the Mechanistic Links between Diet, Obesity, Type II Diabetes, and CancerLgl reduces endosomal vesicle acidification and Notch signaling by promoting the interaction between Vap33 and the V-ATPase complex
P50
Q28201770-F42F65B1-B646-49AD-B05D-1E9A27E0D866Q28206982-49F67D54-A3B0-4CB4-BD69-7818C61F22B5Q28590994-1BC91D5F-EC41-4D9D-AF1A-59ED0DAB7849Q33820271-54D06514-7DA8-4A17-AD20-F39F19670658Q36185779-04E245AB-32DD-4ECB-BF1D-53EA52A5BDB2Q37264327-D4D2595D-FEF6-4037-AF82-44231A85F4F0Q37783515-81E7360C-35E1-4D4C-8BEA-56D037957387Q40691469-C3F05720-6C7A-45D3-975D-A18DDEBE2EF3Q40836025-A63A136C-DE9D-4372-B025-BCA0A53961C0Q41380844-5F1312B7-E79A-489A-9831-499DA1C06C66Q45741872-0B99F859-8C30-477E-A191-C7A08B62C33DQ47071867-A89398B9-C734-4C9B-9DE6-3078F375232FQ48182995-9B6C3950-F3C4-4BA7-807A-B7258A804E22Q52708462-78510555-085F-4C1C-B0D6-26975004D307Q60950083-08017AA9-2BAD-44EF-866B-A6760ADA3B78Q60950728-78FEDAB8-71F1-4D82-9FC4-D1D45DEC5CD5
P50
description
researcher
@en
name
Linda M. Parsons
@en
Parsons LM
@nl
type
label
Linda M. Parsons
@en
Parsons LM
@nl
prefLabel
Linda M. Parsons
@en
Parsons LM
@nl
P106
P31
P496
0000-0002-7738-8280