about
Interactions between PD-1 and PD-L1 promote tolerance by blocking the TCR-induced stop signal.A peptide prime-DNA boost immunization protocol provides significant benefits as a new generation Aβ42 DNA vaccine for Alzheimer disease.Differential induction of IgE-mediated anaphylaxis after soluble vs. cell-bound tolerogenic peptide therapy of autoimmune encephalomyelitis.DNA beta-amyloid(1-42) trimer immunization for Alzheimer disease in a wild-type mouse model.Functional role of epitope spreading in the chronic pathogenesis of autoimmune and virus-induced demyelinating diseases.Testing effects of glatiramer acetate and fingolimod in an infectious model of CNS immune surveillance.T cell subsets and their signature cytokines in autoimmune and inflammatory diseases.A Single Amino Acid Substitution Prevents Recognition of a Dominant Human Aquaporin-4 Determinant in the Context of HLA-DRB1*03:01 by a Murine TCR.Discordant effects of anti-VLA-4 treatment before and after onset of relapsing experimental autoimmune encephalomyelitis.Insulin-induced remission in new-onset NOD mice is maintained by the PD-1-PD-L1 pathway.Immunologic mechanisms of multiple sclerosis.Immune surveillance of the central nervous system in multiple sclerosis--relevance for therapy and experimental models.The detrimental impact of persistent vs an isolated occurrence of de novo donor-specific antibodies on intermediate-term renal transplant outcomes.Early clearance vs persistence of de novo donor-specific antibodies following lung transplantation.CTLA-4 regulates expansion and differentiation of Th1 cells following induction of peripheral T cell tolerance.CTLA-4 downregulates epitope spreading and mediates remission in relapsing experimental autoimmune encephalomyelitisPresenilin1 regulates Th1 and Th17 effector responses but is not required for experimental autoimmune encephalomyelitisPathologic role and temporal appearance of newly emerging autoepitopes in relapsing experimental autoimmune encephalomyelitisThe functional significance of epitope spreading and its regulation by co-stimulatory molecules200 years after Darwin
P50
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P50
description
researcher
@en
name
T N Eagar
@en
T N Eagar
@nl
type
label
T N Eagar
@en
T N Eagar
@nl
prefLabel
T N Eagar
@en
T N Eagar
@nl
P106
P31
P496
0000-0002-9738-544X