about
TRAF2; TRAF6TRAF2:cIAP1;2TRAF1:TRAF2:K63polyUb-cIAP1;2K63polyUb-TRAF2;K63polyUb-TRAF6;K63polyUb-RIPK1;K63polyUb-IKBKGTRAF2;TRAF6;IKBKG;RIPK1PolyUb-TRAF2;PolyUb-TRAF6USP48:TRAF2TRAF2:TRADD:RIP1(325-671)TRAF2:TRADD:RIPK1TNF-alpha:TNFR1:TRADD:RIPK1:TRAF2TNF-alpha:TNFR1:TRADD:K63polyUb-RIPK1:BIRC2;3;4TNFalpha:TNFR1:TRADD:TRAF2:TRAF1:RIPK1TNF:TNFR1 binds TRADD; TRAF2 and RIPK1TRAF1 binds TRAF2 within TNFR1 signaling complex
P527
P688
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1Activation of caspase-12, an endoplastic reticulum (ER) resident caspase, through tumor necrosis factor receptor-associated factor 2-dependent mechanism in response to the ER stressA novel TNF receptor family member binds TWEAK and is implicated in angiogenesisTNF-RII and c-IAP1 mediate ubiquitination and degradation of TRAF2Selective regulation of tumor necrosis factor-induced Erk signaling by Src family kinases and the T cell protein tyrosine phosphataseUrsolic acid induces ER stress response to activate ASK1-JNK signaling and induce apoptosis in human bladder cancer T24 cellsDe-ubiquitination and ubiquitin ligase domains of A20 downregulate NF-kappaB signallingAssociation of beta-arrestin and TRAF6 negatively regulates Toll-like receptor-interleukin 1 receptor signalingTWEAK induces apoptosis through a death-signaling complex comprising receptor-interacting protein 1 (RIP1), Fas-associated death domain (FADD), and caspase-8Roles of CHOP/GADD153 in endoplasmic reticulum stressTAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by receptor activator of NF-kappaBBiochemical aspects of the neuroprotective mechanism of PTEN-induced kinase-1 (PINK1)Asymmetric recruitment of cIAPs by TRAF2Anatomy of TRAF2. Distinct domains for nuclear factor-kappaB activation and association with tumor necrosis factor signaling proteinsA novel family of putative signal transducers associated with the cytoplasmic domain of the 75 kDa tumor necrosis factor receptorEVER2 protein binds TRADD to promote TNF-α-induced apoptosisHuman glutathione S-transferase P1-1 interacts with TRAF2 and regulates TRAF2-ASK1 signalsSphingosine-1-phosphate is a missing cofactor for the E3 ubiquitin ligase TRAF2TRAF family proteins link PKR with NF-kappa B activationThe TRAF6 ubiquitin ligase and TAK1 kinase mediate IKK activation by BCL10 and MALT1 in T lymphocytesMAP3K-related kinase involved in NF-kappaB induction by TNF, CD95 and IL-1A protein-protein interaction map of the TNF-induced NF-κB signal transduction pathway
P921
Q50261581-282EFD3B-E43F-49A8-A00D-C547644BCCC4Q50263897-F076643B-B755-4B48-ACAC-706E13621D9AQ50263905-6F946249-F172-485D-825D-F68165B87D6FQ50268867-DA700F21-CAE5-4625-A2AC-256E853EC825Q50268869-C606EF60-9869-4265-85CF-06C29E88B7D9Q50269022-889A3EE5-57DA-4E9C-8DEA-4D087017E8D2Q50269039-76971288-15FE-49C3-B690-57F7A11C4666Q50270703-52BAC4BA-EF46-4A1F-A47B-3D25548D891AQ50270707-F9753B11-E20A-4680-AE7B-EA2C3A14F55BQ50274349-0E441912-41CD-42F3-962F-10B2468F9EEBQ50274351-D9E9B7A6-9EC8-4D86-9B40-152746C9328DQ50274368-BBC09323-3B07-41A8-A050-6506D4FEA639Q50299344-2AAFCBB8-3E90-4967-B7EE-B56D83ADBF3EQ50299364-3AC30DCD-9749-4C40-93F2-33E0E2D3F783
P527
Q22011167-9EBF4CA9-135E-4DB7-8D7D-9C248177548DQ24291026-CC477EC7-E863-4D30-9DAD-21749732FBA6Q24291951-494930D0-FD28-48D6-8340-021642E1CF2AQ24292505-AB0AD81A-5D90-4E7D-B81D-641104AE4AEEQ24294324-1E780CE4-57C7-4E6E-8FE8-55F91FCB3E22Q24299207-41E4EC8D-AB45-4DBF-B985-C2AE3A813983Q24299573-7616F7A3-8250-44CA-A5D2-8B6DDD0410B3Q24299892-1D0AAB3E-DF2F-4E43-9732-0A0AE2FC9C09Q24300508-508EF396-6B99-4293-BD3E-C620EA1EB2F7Q24302185-8596D25C-7559-4DCD-93E3-6DF9CABB3C05Q24307620-F7A96BA2-C96C-44AB-A5F7-FF4CF968E3B1Q24307730-E7ED79EB-40CF-47B9-AED3-DA57386A5B27Q24310283-90181CC9-919A-40CB-B1BA-DFD0985377F9Q24311703-C9B26ED8-210C-4AC3-A961-E8FEF4C03D48Q24318280-C8F6AB7F-2126-4CD2-8B23-E5D930EF6B1FQ24318990-4ADB6DB4-6BDE-47AF-8121-AFF60AD351CEQ24320308-49ADEDED-4709-4190-BD61-5369A1006085Q24336131-5EBC01A0-7142-470F-8E58-1CF37B42F059Q24338458-D017C2C1-8694-44E6-86A2-BF2183E782E9Q24338639-3B60ECD2-863F-4EBC-B2A4-A29B581DE4C5Q28302936-3138A388-875E-41CE-A991-C4A1543AEE21Q60044295-C2A5352F-0F22-4C4C-BA92-01E0ABB90713
P921
description
Protein in Homo sapiens
@de
mammalian protein found in Homo sapiens
@en
protein
@id
protein
@sv
proteinë
@sq
proteïne in TNF receptor associated factor 2
@nl
protèin
@ace
protéine
@fr
بروتين في الإنسان العاقل
@ar
name
TNF receptor associated factor 2
@en
TNF receptor associated factor 2
@nl
type
label
TNF receptor associated factor 2
@en
TNF receptor associated factor 2
@nl
altLabel
E3 ubiquitin-protein ligase TRAF2
@en
RING-type E3 ubiquitin transferase TRAF2
@en
TNF receptor-associated factor 2
@en
TRAF2
@en
Tumor necrosis factor type 2 receptor-associated protein 3
@en
tumor necrosis factor type 2 receptor associated protein 3
@en
prefLabel
TNF receptor associated factor 2
@en
TNF receptor associated factor 2
@nl
P361
P527
P637
P638
P680
P681
P682
P705
P352
P31
P352
P527
P637
XP_011517276
XP_011517278
XP_011517279
P638
P680
P681
P682
P702
P703
P705
ENSP00000247668
ENSP00000397653
ENSP00000405860
ENSP00000406524