about
The past and future of tuberculosis researchHigh functional diversity in Mycobacterium tuberculosis driven by genetic drift and human demographyConsequences of genomic diversity in Mycobacterium tuberculosisEvolution of drug resistance in tuberculosis: recent progress and implications for diagnosis and therapyWithin Host Evolution Selects for a Dominant Genotype of Mycobacterium tuberculosis while T Cells Increase Pathogen Genetic DiversityImpact of bacterial genetics on the transmission of isoniazid-resistant Mycobacterium tuberculosisGenomic diversity among drug sensitive and multidrug resistant isolates of Mycobacterium tuberculosis with identical DNA fingerprintsIndependent large scale duplications in multiple M. tuberculosis lineages overlapping the same genomic regionUse of whole genome sequencing to determine the microevolution of Mycobacterium tuberculosis during an outbreakCo-evolution of Mycobacterium tuberculosis and Homo sapiensGenotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies.Significant under expression of the DosR regulon in M. tuberculosis complex lineage 6 in sputum.Does M. tuberculosis genomic diversity explain disease diversity?KvarQ: targeted and direct variant calling from fastq reads of bacterial genomes.Lipidomics and genomics of Mycobacterium tuberculosis reveal lineage-specific trends in mycolic acid biosynthesisDiversity of Mycobacterium tuberculosis and drug resistance in different provinces of Papua New GuineaLong-term dominance of Mycobacterium tuberculosis Uganda family in peri-urban Kampala-Uganda is not associated with cavitary diseaseEvolutionary history and global spread of the Mycobacterium tuberculosis Beijing lineage.Whole-genome sequencing of rifampicin-resistant Mycobacterium tuberculosis strains identifies compensatory mutations in RNA polymerase genes.Old and new selective pressures on Mycobacterium tuberculosis.The W-Beijing lineage of Mycobacterium tuberculosis overproduces triglycerides and has the DosR dormancy regulon constitutively upregulatedA single-nucleotide-polymorphism real-time PCR assay for genotyping of Mycobacterium tuberculosis complex in peri-urban Kampala.Distribution and transmission of Mycobacterium tuberculosis complex lineages among children in peri-urban Kampala, Uganda.Genomic epidemiology of multidrug-resistant Mycobacterium tuberculosis during transcontinental spreadImpact of in vitro evolution on antigenic diversity of Mycobacterium bovis bacillus Calmette-Guerin (BCG)Large sequence polymorphisms classify Mycobacterium tuberculosis strains with ancestral spoligotyping patterns.Spatio-Temporal Distribution of Mycobacterium tuberculosis Complex Strains in GhanaPopulation Genomics of Mycobacterium tuberculosis in Ethiopia Contradicts the Virgin Soil Hypothesis for Human Tuberculosis in Sub-Saharan Africa.M. tuberculosis T Cell Epitope Analysis Reveals Paucity of Antigenic Variation and Identifies Rare Variable TB Antigens.Strain classification of Mycobacterium tuberculosis: congruence between large sequence polymorphisms and spoligotypes.Global phylogeography of Mycobacterium tuberculosis and implications for tuberculosis product development.Mycobacterial lineages causing pulmonary and extrapulmonary tuberculosis, Ethiopia.Detection and characterization of drug-resistant conferring genes in Mycobacterium tuberculosis complex strains: A prospective study in two distant regions of Ghana.Prevalence of fluoroquinolone resistance among tuberculosis patients in Shanghai, China.Mapping of genotype-phenotype diversity among clinical isolates of mycobacterium tuberculosis by sequence-based transcriptional profilingEpistasis between antibiotic resistance mutations drives the evolution of extensively drug-resistant tuberculosis.Sequence diversity in the pe_pgrs genes of Mycobacterium tuberculosis is independent of human T cell recognitionInfectiousness, reproductive fitness and evolution of drug-resistant Mycobacterium tuberculosis.Clinical implications of molecular drug resistance testing for Mycobacterium tuberculosis: a TBNET/RESIST-TB consensus statement.Consensus numbering system for the rifampicin resistance-associated rpoB gene mutations in pathogenic mycobacteria.
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wetenschapper
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S Gagneux
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S Gagneux
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S Gagneux
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S Gagneux
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S Gagneux
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S Gagneux
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P106
P31
P496
0000-0001-7783-9048