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The potential of liposomes with carbonic anhydrase IX to deliver anticancer ingredients to cancer cells in vivoSimultaneous quantification of five major biologically active ingredients of saffron by high-performance liquid chromatographyData showing the circumvention of oxaliplatin resistance by vatalanib in colon cancer.Selective and sensitive determination of bis(7)-tacrine, a high erythrocyte binding acetylcholinesterase inhibitor, in rat plasma by high-performance liquid chromatography-tandem mass spectrometry.Controllable drug release and simultaneously carrier decomposition of SiO2-drug composite nanoparticles.Rapid endosomal escape of prickly nanodiamonds: implications for gene delivery.Naturally occurring proteinaceous nanoparticles in Coptidis Rhizoma extract act as concentration-dependent carriers that facilitate berberine absorption.Pelitinib (EKB-569) targets the up-regulation of ABCB1 and ABCG2 induced by hyperthermia to eradicate lung cancerBlood pyrrole-protein adducts as a diagnostic and prognostic index in pyrrolizidine alkaloid-hepatic sinusoidal obstruction syndrome.Quality assurance and safety of herbal dietary supplements.Structure-activity relationships of the glucuronidation of flavonoids by human glucuronosyltransferases.Unambiguous observation of shape effects on cellular fate of nanoparticles.Pharmacological effects and pharmacokinetics properties of Radix Scutellariae and its bioactive flavones.Importance of metabolic activation study to the safe use of Chinese herbal medicines.Transporter modulation by Chinese herbal medicines and its mediated pharmacokinetic herb-drug interactions.Imaging-guided delivery of RNAi for anticancer treatment.Vatalanib sensitizes ABCB1 and ABCG2-overexpressing multidrug resistant colon cancer cells to chemotherapy under hypoxia.Anti-metastatic effect and mechanisms of Wenshen Zhuanggu Formula in human breast cancer cells.Insights into the central pathways involved in the emetic and behavioural responses to exendin-4 in the ferret.Reversal of P-glycoprotein-mediated multidrug resistance by a synthetic α-aminoxy peptidomimetic.Study of the anti-proliferative effects and synergy of phthalides from Angelica sinensis on colon cancer cells.Anti-inflammatory Inositol Derivatives from the Whole Plant of Inula cappa.Differential hypoglycaemic, anorectic, autonomic and emetic effects of the glucagon-like peptide receptor agonist, exendin-4, in the conscious telemetered ferret.Comparison of intestinal absorption and disposition of structurally similar bioactive flavones in Radix Scutellariae.Mechanistic study on the intestinal absorption and disposition of baicalein.Role of intestinal first-pass metabolism of baicalein in its absorption process.Cytotoxicity of pyrrolizidine alkaloid in human hepatic parenchymal and sinusoidal endothelial cells: Firm evidence for the reactive metabolites mediated pyrrolizidine alkaloid-induced hepatotoxicity.Lack of metabolic activation and predominant formation of an excreted metabolite of nontoxic platynecine-type pyrrolizidine alkaloids.Olvanil, a non-pungent vanilloid enhances the gastrointestinal toxicity of cisplatin in the ferret.Polyoxypregnane steroids from the stems of Marsdenia tenacissima.Influence of mefenamic acid on the intestinal absorption and metabolism of three bioactive flavones in Radix Scutellariae and potential pharmacological impact.Assessment of pyrrolizidine alkaloid-induced toxicity in an in vitro screening model.A generic multiple reaction monitoring based approach for plant flavonoids profiling using a triple quadrupole linear ion trap mass spectrometry.Metabolic formation of DHP-derived DNA adducts from a representative otonecine type pyrrolizidine alkaloid clivorine and the extract of Ligularia hodgsonnii hook.A catenary model to study transport and conjugation of baicalein, a bioactive flavonoid, in the Caco-2 cell monolayer: demonstration of substrate inhibition.High-performance liquid chromatographic method for simultaneous determination of baicalein and baicalein 7-glucuronide in rat plasma.Synergistic interaction between the Ligusticum chuanxiong constituent butylidenephthalide and the nitric oxide donor sodium nitroprusside in relaxing rat isolated aorta.Alkaloids from roots of Stemona sessilifolia and their antitussive activities.Investigation of association of chemical profiles with the tracheobronchial relaxant activity of Chinese medicinal herb Beimu derived from various Fritillaria species.First evidence of pyrrolizidine alkaloid N-oxide-induced hepatic sinusoidal obstruction syndrome in humans.
P50
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P50
description
researcher
@en
name
G Lin
@nl
Ge Lin
@en
type
label
G Lin
@nl
Ge Lin
@en
altLabel
G Lin
@en
prefLabel
G Lin
@nl
Ge Lin
@en
P106
P31
P496
0000-0002-4586-2603