about
Targeted therapy for hepatocellular carcinoma: novel agents on the horizonGSK-3 as potential target for therapeutic intervention in cancerAdvances in targeting signal transduction pathwaysRoles of GSK-3 and microRNAs on epithelial mesenchymal transition and cancer stem cellsNanoassemblies Based on Supramolecular Complexes of Nonionic Amphiphilic Cyclodextrin and Sorafenib as Effective Weapons to Kill Human HCC Cells.Cloning and expression of a type IX-like collagen in tissues of the ascidian Ciona intestinalis.Targeting the Raf/MEK/ERK pathway with small-molecule inhibitors.Heat shock protein 70 serum levels differ significantly in patients with chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma.Interleukin-6 and its soluble receptor in patients with liver cirrhosis and hepatocellular carcinoma.Deregulation of the EGFR/PI3K/PTEN/Akt/mTORC1 pathway in breast cancer: possibilities for therapeutic intervention.NAIP-deltaEx10-11: a novel splice variant of the apoptosis inhibitor NAIP differently expressed in drug-sensitive and multidrug-resistant HL60 leukemia cells.Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascade inhibitors: how mutations can result in therapy resistance and how to overcome resistance.Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging.Cytotoxic activity of the novel small molecule AKT inhibitor SC66 in hepatocellular carcinoma cellsRas/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR inhibitors: rationale and importance to inhibiting these pathways in human health.Expression of IAPs and alternative splice variants in hepatocellular carcinoma tissues and cells.Correlation between expression of cyclooxygenase-2 and the presence of inflammatory cells in human primary hepatocellular carcinoma: possible role in tumor promotion and angiogenesis.Management of Liver Failure: From Transplantation to Cell-Based Therapy.Mutations and deregulation of Ras/Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR cascades which alter therapy response.Effects of ectopic expression of NGAL on doxorubicin sensitivity.A PTEN inhibitor displays preclinical activity against hepatocarcinoma cellsDiverse roles of GSK-3: tumor promoter-tumor suppressor, target in cancer therapy.Targeting breast cancer initiating cells: advances in breast cancer research and therapy.Roles of signaling pathways in drug resistance, cancer initiating cells and cancer progression and metastasis.Effects of mutations in Wnt/β-catenin, hedgehog, Notch and PI3K pathways on GSK-3 activity-Diverse effects on cell growth, metabolism and cancer.Roles of EGFR and KRAS and their downstream signaling pathways in pancreatic cancer and pancreatic cancer stem cells.Roles of NGAL and MMP-9 in the tumor microenvironment and sensitivity to targeted therapy.Critical Roles of EGFR Family Members in Breast Cancer and Breast Cancer Stem Cells: Targets for Therapy.Lipid nanocarriers containing sorafenib inhibit colonies formation in human hepatocarcinoma cells.Entrapment of an EGFR inhibitor into nanostructured lipid carriers (NLC) improves its antitumor activity against human hepatocarcinoma cells.Roles of TP53 in determining therapeutic sensitivity, growth, cellular senescence, invasion and metastasis.Regulation of GSK-3 activity by curcumin, berberine and resveratrol: Potential effects on multiple diseases.Pivotal roles of glycogen synthase-3 in hepatocellular carcinoma.Transcriptional regulation of miR-224 upregulated in human HCCs by NFκB inflammatory pathways.Antitumor effects of dehydroxymethylepoxyquinomicin, a novel nuclear factor-kappaB inhibitor, in human liver cancer cells are mediated through a reactive oxygen species-dependent mechanism.Aromatase and amphiregulin are correspondingly expressed in human liver cancer cells.GSK-3beta is a critical mediator of tetrandrine induced cell cycle arrest and cytotoxicity.Histamine and spontaneously released mast cell granules affect the cell growth of human hepatocellular carcinoma cells.Novel cationic solid-lipid nanoparticles as non-viral vectors for gene delivery.Nanostructured lipid carriers-containing anticancer compounds: preparation, characterization, and cytotoxicity studies.
P50
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P50
name
Melchiorre Cervello
@en
Melchiorre Cervello
@nl
type
label
Melchiorre Cervello
@en
Melchiorre Cervello
@nl
prefLabel
Melchiorre Cervello
@en
Melchiorre Cervello
@nl