about
Genomic Sequence of an Otitis Media Isolate of Nontypeable Haemophilus influenzae: Comparative Study with H. influenzae Serotype d, Strain KW20The Chinchilla Research Resource Database: resource for an otolaryngology disease model.Antibody to a conserved antigenic target is protective against diverse prokaryotic and eukaryotic pathogensPanel 4: Recent advances in otitis media in molecular biology, biochemistry, genetics, and animal models.Respiratory syncytial virus promotes Moraxella catarrhalis-induced ascending experimental otitis mediaPhosphorylcholine decreases early inflammation and promotes the establishment of stable biofilm communities of nontypeable Haemophilus influenzae strain 86-028NP in a chinchilla model of otitis media.A biphasic epigenetic switch controls immunoevasion, virulence and niche adaptation in non-typeable Haemophilus influenzae.Structural stability of Burkholderia cenocepacia biofilms is reliant on eDNA structure and presence of a bacterial nucleic acid binding proteinNontypeable Haemophilus influenzae gene expression induced in vivo in a chinchilla model of otitis media.A mutation in the sap operon attenuates survival of nontypeable Haemophilus influenzae in a chinchilla model of otitis media.Improving patient care via development of a protein-based diagnostic test for microbe-specific detection of chronic rhinosinusitisImmunopathogenesis of polymicrobial otitis media.Panel 6: Vaccines.Demonstration of Type IV pilus expression and a twitching phenotype by Haemophilus influenzae.The multifunctional host defense peptide SPLUNC1 is critical for homeostasis of the mammalian upper airwayChinchilla and murine models of upper respiratory tract infections with respiratory syncytial virus.Mapping the anatomy of respiratory syncytial virus infection of the upper airways in chinchillas (Chinchilla lanigera).Nontypeable Haemophilus influenzae adheres to intercellular adhesion molecule 1 (ICAM-1) on respiratory epithelial cells and upregulates ICAM-1 expression.ModA2 Phasevarion Switching in Nontypeable Haemophilus influenzae Increases the Severity of Experimental Otitis MediaRecent advances in otitis media. 4. Anatomy, cell biology, pathology, and animal models.Recent advances in otitis media. 5. Molecular biology and biochemistry.Recent advances in otitis media. 6. Microbiology and immunology.Recent advances in otitis media. 7. Vaccine.Panel 3: Recent advances in anatomy, pathology, and cell biology in relation to otitis media pathogenesis.Heme utilization by nontypeable Haemophilus influenzae is essential and dependent on Sap transporter functionCopy number variation of the beta defensin gene cluster on chromosome 8p influences the bacterial microbiota within the nasopharynx of otitis-prone children.Innate immunity and the role of defensins in otitis media.Antibodies against the majority subunit of type IV Pili disperse nontypeable Haemophilus influenzae biofilms in a LuxS-dependent manner and confer therapeutic resolution of experimental otitis media.A member of the cathelicidin family of antimicrobial peptides is produced in the upper airway of the chinchilla and its mRNA expression is altered by common viral and bacterial co-pathogens of otitis media.DNABII proteins play a central role in UPEC biofilm structureDeveloping animal models for polymicrobial diseases.Use of the chinchilla model for nasopharyngeal colonization to study gene expression by Moraxella catarrhalisExpression, purification, crystallization and preliminary crystallographic analysis of PilA from the nontypeable Haemophilus influenzae type IV pilus.Therapeutic Transcutaneous Immunization with a Band-Aid Vaccine Resolves Experimental Otitis Media.Selection and Counterselection of Hia Expression Reveals a Key Role for Phase-Variable Expression of Hia in Infection Caused by Nontypeable Haemophilus influenzae.Recent advances in otitis media. 3. Animal models; anatomy and pathology; pathogenesis; cell biology and genetics.Recent advances in otitis media. 4A. Molecular biology.Recent advances in otitis media. 4B. Biochemistry.Recent advances in otitis media. 4C. Interaction between middle ear and inner ear in otitis media.Recent advances in otitis media. 6. Vaccine.
P50
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P50
name
Lauren O Bakaletz
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Lauren O Bakaletz
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type
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Lauren O Bakaletz
@en
Lauren O Bakaletz
@nl
prefLabel
Lauren O Bakaletz
@en
Lauren O Bakaletz
@nl